State Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.
Nanotechnology. 2011 Jul 29;22(30):305307. doi: 10.1088/0957-4484/22/30/305307. Epub 2011 Jul 1.
In this paper, we report on a novel strategy for the preparation of silver nanoparticle-doped SiO(2) microspheres (Ag-SMSs) with an interesting strawberry-like morphology using a simple and efficient electrospraying method. SEM (scanning electron microscopy), TEM (transmission electron microscopy), XRD (x-ray diffraction), EDS (energy-dispersive spectroscopy) and UV-vis spectra (ultraviolet-visible spectra) were applied to investigate the morphology, structure, composition and optical properties of the hybrid microspheres, and E. coli (Escherichia coli) was used as a model microbe to evaluate their antibacterial ability. The results showed that the Ag-SMSs were environmentally stable and washing resistant. The Ag-SMSs exhibited effective inhibition against proliferation of E. coli, and their antibacterial ability could be well preserved for a long time. The environmental stability, washing resistance, efficient antibacterial ability and simple but productive preparation method endowed the Ag-SMSs with great potential for practical biomedical applications.
本文报道了一种新颖的策略，通过简单有效的静电纺丝方法制备具有有趣草莓状形态的银纳米粒子掺杂二氧化硅微球（Ag-SMSs）。SEM（扫描电子显微镜）、TEM（透射电子显微镜）、XRD（X 射线衍射）、EDS（能谱）和 UV-vis 光谱（紫外-可见光谱）用于研究混合微球的形态、结构、组成和光学性质，并用大肠杆菌（Escherichia coli）作为模型微生物来评估其抗菌能力。结果表明，Ag-SMSs 具有环境稳定性和耐洗性。Ag-SMSs 对大肠杆菌的增殖表现出有效抑制作用，其抗菌能力可以长时间很好地保持。环境稳定性、耐洗性、高效的抗菌能力以及简单但多产的制备方法使 Ag-SMSs 在实际生物医学应用中具有巨大的潜力。
