Jeanneret L Achtari, Schneider M P, Troxler S, Bugnon O, Lüthi F
Centre pluridisciplinaire d'oncologie, CHUV, Lausanne.
Rev Med Suisse. 2011 May 25;7(296):1154-8, 1160.
Medication adherence is a well-known risk factor in internal medicine. However in oncology this dimension is emerging due to the increasing number of oral formulations. First results in the oral oncology literature suggest that patients' ability to cope with medical prescription decreases with time. This might preclude patients from reaching clinical outcomes. Factors impacting on medication adherence to oral oncology treatments have not been yet extensively described neither strategies to address them and support patient's needs. Oncologists and pharmacists in our University outpatient settings performed a pilot study which aimed at measuring and facilitating adherence to oral oncology treatments and at understanding determinants of patient's adherence. The ultimate purpose of such a patient-centered and interdisciplinary collaboration would be to promote patient self-management and complement the standard medical follow-up.
药物依从性是内科领域一个众所周知的风险因素。然而，在肿瘤学领域，由于口服制剂数量的增加，这一维度正逐渐显现出来。肿瘤学口服药物文献的初步结果表明，患者应对医嘱的能力会随着时间的推移而下降。这可能会妨碍患者达到临床治疗效果。影响口服肿瘤治疗药物依从性的因素尚未得到广泛描述，解决这些因素并满足患者需求的策略也未得到广泛描述。我们大学门诊的肿瘤学家和药剂师进行了一项试点研究，旨在衡量并促进口服肿瘤治疗的依从性，并了解患者依从性的决定因素。这种以患者为中心的跨学科合作的最终目的是促进患者自我管理，并补充标准的医学随访。
