Ben Gurion University, Department of Electro-Optic Engineering and Ilse Katz Institute for Nanoscale Science and Technology, Beer Sheva 84105, Israel.
J Biomed Opt. 2011 Jun;16(6):067006. doi: 10.1117/1.3592779.
The human skin is modeled as a stack of homogeneous layers in the terahertz and submillimeter waves regions with some anisotropy due to the helical sweat glands and other elongated entities. A dielectric model for the skin is presented, valid for a wider frequency range (up to the terahertz region) taking into account the dispersive nature of the effective conductivity. Polarized reflectivity and generalized ellipsometric parameters are calculated versus angle and wavelength. Recent studies have claimed that the helical sweat ducts act as an array of low-Q helical antennae and are dominant in shaping the spectral response in the sub-terahertz region. We found that water absorption, dispersion and multiple interference effects play the major role in shaping the spectrum without the need for the assumption of the sweat ducts acting as low-Q helical antennae. High sensitivities to the water content are found particularly in the ellipsometric parameters at large incidence angles. Hence a new methodology is proposed to detect skin cancer using variable angle ellipsometry or polarized reflectometry. The parameter found with the highest sensitivity to water content is cos Δ(pp) with Δ(pp) being the phase of the on-diagonal reflection matrix ratio between p-to-p polarization.
人体皮肤在太赫兹和亚毫米波区域被建模为具有各向异性的均匀层堆栈,这是由于螺旋形汗腺和其他伸长实体造成的。提出了一种适用于更宽频率范围(高达太赫兹区域)的皮肤介电模型,该模型考虑了有效电导率的色散性质。计算了极化反射率和广义椭圆偏振参数随角度和波长的变化。最近的研究声称,螺旋形汗腺管充当低 Q 螺旋天线阵列,并在亚太赫兹区域的光谱响应中起主导作用。我们发现,水吸收、色散和多次干涉效应在没有假设汗腺管作为低 Q 螺旋天线的情况下,在形成光谱中起着主要作用。在大入射角处,特别是在椭圆偏振参数中,对含水量的灵敏度很高。因此,提出了一种使用变角椭圆偏振术或偏振反射术检测皮肤癌的新方法。对含水量最敏感的参数是 cosΔ(pp),其中Δ(pp)是 p 到 p 偏振比的对角反射矩阵比的相位。