Prose N S, von Knebel-Doeberitz C, Miller S, Milburn P B, Heilman E
Department of Dermatology, State University of New York-Health Science Center, Brooklyn.
J Am Acad Dermatol. 1990 Nov;23(5 Pt 2):978-81. doi: 10.1016/0190-9622(90)70318-c.
Numerous flat and tinea versicolor-like warts developed on the face, trunk, and upper extremities of a 10-year-old boy with human immunodeficiency virus infection. Nucleic acid analysis of involved skin revealed human papillomavirus type 5, which has sometimes been associated with epidermodysplasia verruciformis. This human papillomavirus type has also been described in patients with common variable immunodeficiency and dyskeratosis congenita and in renal allograft recipients. Human immunodeficiency virus infection should be added to the list of immune-related disorders that predispose to widespread flat warts.
一名感染人类免疫缺陷病毒的10岁男孩的面部、躯干和上肢出现了许多扁平的、花斑癣样的疣。对受累皮肤进行核酸分析发现了5型人乳头瘤病毒,该病毒有时与疣状表皮发育不良有关。这种人乳头瘤病毒也在常见可变免疫缺陷、先天性角化不良患者以及肾移植受者中被描述过。人类免疫缺陷病毒感染应被列入易导致广泛扁平疣的免疫相关疾病名单中。