Kitayama Y, Tsukada S
Arch Dermatol. 1983 Jan;119(1):8-12. doi: 10.1001/archderm.119.1.8.
We have seen 11 cases of congenital onychodysplasia over the past six years. Associated anomalies were present in six patients, most of whom had an anomaly of the hand. Roentgenograms of the affected fingers showed hypoplasia, narrowing at the distal third of the distal phalanx, and bifurcation of the distal phalanx. The etiology of this condition is unknown, but clinical study suggested that ischemia of the finger at a certain period of embryonic life might play an important part in its pathogenesis.
在过去六年中，我们共诊治了11例先天性甲发育异常患者。6例患者伴有其他异常，其中大多数存在手部异常。受累手指的X线片显示发育不全、远节指骨远端三分之一处变窄以及远节指骨分叉。这种疾病的病因尚不清楚，但临床研究表明，胚胎期某个阶段手指缺血可能在其发病机制中起重要作用。
