Department of Nutrition & Dietetics, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050 Sydney, Australia.
Clin Nutr. 2011 Dec;30(6):774-9. doi: 10.1016/j.clnu.2011.03.003. Epub 2011 Jul 1.
BACKGROUND & AIMS: Major upper gastrointestinal surgery results in permanent alterations to the gastrointestinal tract, and previously been shown to impair nutritional status. The aim of this study was to assess long term nutritional status and quality of life in people having had major upper gastrointestinal surgery, and the relationship between the two measures.
People having had major upper gastrointestinal surgery greater than 6 months ago were recruited. Nutrition assessment included weight, anthropometry, Subjective Global Assessment, dietary intake and assessment of gastrointestinal symptoms; quality of life was assessed using the EORTC QLQ-C30 questionnaire. Associations between nutritional status, type of surgery and quality of life were analysed.
Thirty people were recruited with fourteen people showing a degree of malnutrition according to subjective global assessment. Total gastrectomy and oesophagectomy surgery resulted in significantly higher percent weight loss than those having undergone pancreaticoduodenectomy (p = 0.01). Subjective global assessment correlated with quality of life (p = 0.003). Subjective global assessment and gastrointestinal symptoms were both significant variables in explaining quality of life (p < 0.001).
Nutritional status in this group was significantly compromised, and impacted on quality of life. Individualised nutrition intervention to address malnutrition and gastrointestinal symptoms should be integrated into post surgery management.
上消化道大手术后会导致胃肠道永久改变，并已证实会损害营养状况。本研究旨在评估接受过上消化道大手术的人群的长期营养状况和生活质量，并探讨两者之间的关系。
招募了上消化道大手术 6 个月以上的患者。营养评估包括体重、人体测量学、主观整体评估、饮食摄入和胃肠道症状评估；使用 EORTC QLQ-C30 问卷评估生活质量。分析了营养状况、手术类型和生活质量之间的关系。
共招募了 30 名患者，其中 14 名患者根据主观整体评估显示存在一定程度的营养不良。全胃切除术和食管切除术的体重百分比下降明显高于胰十二指肠切除术（p = 0.01）。主观整体评估与生活质量相关（p = 0.003）。主观整体评估和胃肠道症状都是解释生活质量的重要变量（p < 0.001）。
该组患者的营养状况明显受损，并影响生活质量。应将针对营养不良和胃肠道症状的个体化营养干预纳入术后管理中。
