Department of Esophageal Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-Gun, Shizuoka, 411-8777, Japan.
Esophagus. 2019 Oct;16(4):408-412. doi: 10.1007/s10388-019-00681-0. Epub 2019 Jun 26.
Esophagectomy is a highly invasive procedure for patients aged > 70 years. Here, we compared the actual nutritional status of older and younger patients who underwent esophagectomy.
A total of 118 patients who underwent radical esophagectomy between April 2013 and December 2016 were enrolled and divided into two groups based on age: group A (n = 41; ≥ 70 years) and group B (n = 77; < 70 years). Data pertaining to body mass index and nutritional variables (albumin; total cholesterol; cholinesterase; and prealbumin) were retrospectively analyzed preoperatively and at 3, 6, and 12 months postoperatively.
Significant preoperative between-group differences were found in the cholinesterase, albumin, and prealbumin levels. The body mass index gradually decreased over the first 12 months after surgery in both groups, without significant between-group differences. Significant differences were observed in prealbumin and cholinesterase levels at 3 months postoperatively. 1 year postoperatively, both groups showed slight improvements; however, the between-group differences were not statistically significant. Group A had a significantly lower amount of the degree of decrement of BMI and chE than group B.
Thus, patients aged > 70 years can recover within 12 months of esophagectomy.
对于年龄大于 70 岁的患者，食管切除术是一种高度侵袭性的手术。在这里，我们比较了接受食管切除术的老年患者和年轻患者的实际营养状况。
共纳入 118 例 2013 年 4 月至 2016 年 12 月期间接受根治性食管切除术的患者，根据年龄分为两组：A 组（n = 41；年龄≥70 岁）和 B 组（n = 77；年龄<70 岁）。回顾性分析了术前及术后 3、6 和 12 个月的体质量指数和营养变量（白蛋白、总胆固醇、胆碱酯酶和前白蛋白）的数据。
术前两组间胆碱酯酶、白蛋白和前白蛋白水平存在显著差异。两组患者的体质量指数在术后 12 个月内逐渐下降，但组间无显著差异。术后 3 个月，前白蛋白和胆碱酯酶水平差异显著。术后 1 年，两组均有轻微改善，但组间差异无统计学意义。A 组 BMI 和 chE 的下降程度明显低于 B 组。
因此，年龄大于 70 岁的患者可以在食管切除术后 12 个月内恢复。
