Cardiology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Can J Cardiol. 2012 Jan-Feb;28(1):80-6. doi: 10.1016/j.cjca.2011.02.001. Epub 2011 Jul 2.
The aim of this study was to compare 3 different available methods for estimating left ventricular end-diastolic pressure (LVEDP) noninvasively in patients with coronary artery disease and preserved left ventricular ejection fraction (EF).
We used 3 equations for noninvasive estimation of LVEDP: The equation of Mulvagh et al., LVEDP(1) = 46 - 0.22 (IVRT) - 0.10 (AFF) - 0.03 (DT) - (2 ÷ E/A) + 0.05 MAR; the equation of Stork et al., LVEDP(2) = 1.06 + 15.15 × Ai/Ei; and the equation of Abd-El-Aziz, LVEDP(3) = [0.54 (MABP) × (1 - EF)] - 2.23. (
A, A-wave velocity; AFF, atrial filling fraction; Ai, time velocity integral of A wave; DT, deceleration time; E, E-wave velocity; Ei, time velocity integral of E wave; IVRT, isovolumic relaxation time; MABP, mean arterial blood pressure; MAR, time from termination of mitral flow to the electrocardiographic R wave; Ti, time velocity integral of total wave.)
LVEDP measured by catheterization was correlated with LVEDP(1) (r = 0.52, P < 0.001), LVEDP(2) (r = 0.31, P < 0.05), and LVEDP(3) (r = 0.81, P < 0.001).
The equation described by Abd-El-Aziz, LVEDP = [0.54 MABP × (1 - EF)] - 2.23, appears to be the most accurate, reliable, and easily applied method for estimating LVEDP noninvasively in patients with preserved left ventricular ejection fraction and an LVEDP < 20 mm Hg.
本研究旨在比较 3 种不同的无创方法，用于估算冠状动脉疾病和左心室射血分数（EF）正常的患者的左心室舒张末期压（LVEDP）。
我们使用 3 个方程来无创估算 LVEDP：Mulvagh 等的方程，LVEDP(1) = 46 - 0.22 (IVRT) - 0.10 (AFF) - 0.03 (DT) - (2 ÷ E/A) + 0.05 MAR；Stork 等的方程，LVEDP(2) = 1.06 + 15.15 × Ai/Ei；以及 Abd-El-Aziz 的方程，LVEDP(3) = [0.54 (MABP) × (1 - EF)] - 2.23。（缩写：A，A 波速度；AFF，心房充盈分数；Ai，A 波时速度积分；DT，减速时间；E，E 波速度；Ei，E 波时速度积分；IVRT，等容舒张时间；MABP，平均动脉血压；MAR，从二尖瓣血流终止到心电图 R 波的时间；Ti，总波时速度积分。）
导管测量的 LVEDP 与 LVEDP(1)（r = 0.52，P < 0.001）、LVEDP(2)（r = 0.31，P < 0.05）和 LVEDP(3)（r = 0.81，P < 0.001）相关。
Abd-El-Aziz 描述的方程，LVEDP = [0.54 MABP × (1 - EF)] - 2.23，似乎是一种最准确、可靠和易于应用的方法，用于估算 EF 正常且 LVEDP < 20 mmHg 的患者的 LVEDP。
