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脑室注射血管加压素和催产素对诱发舌肌抽搐的影响。

Effect of vasopressin and oxytocin perfusion of the cerebral ventricles on evoked tongue jerks.

作者信息

Leśnik H

出版信息

Acta Physiol Pol. 1978 Jul-Aug;29(4):373-7.

PMID:217238
Abstract

The effect of increased concentration of vasopressin and oxytocin in the cerebrospinal fluid on the excitability of the hypoglossal nerve nucleus was investigated. The experiments were carried out on rats under chloralose anaesthesia. Retractory jerks of the outstretched tongue were evoked by supra- or infraorbital nerve stimulation during perfusion of the cerebral ventricles with McIlwain-Rodnight solution. The solution contained synthetic arginine vasopressin 0.05 U/ml or synthetic oxytocin 0.05 U/ml. Perfusion of the ventricles with vasopressin increased and perfusion with oxytocin decreased the evoked tongue jerks.

摘要

研究了脑脊液中血管加压素和催产素浓度升高对舌下神经核兴奋性的影响。实验在水合氯醛麻醉的大鼠身上进行。在用麦基尔韦恩 - 罗德奈特溶液灌注脑室期间,通过眶上或眶下神经刺激诱发伸出舌头的重复性抽搐。该溶液含有0.05 U/ml的合成精氨酸血管加压素或0.05 U/ml的合成催产素。用血管加压素灌注脑室会增加,而用催产素灌注会减少诱发的舌头抽搐。

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