Manji H, Schwartz M S, McKeran R O
Department of Neurology, Atkinson Morley's Hospital, Wimbledon, London, UK.
J Neurol. 1990 Aug;237(5):324-5. doi: 10.1007/BF00314753.
A patient with small cell carcinoma of the lung developed asymptomatic autonomic neuropathy, inappropriate antidiuretic hormone (ADH) secretion and Lambert Eaton myasthenic syndrome. The autonomic neuropathy and inappropriate ADH secretion were present at the time of diagnosis of the tumour. Following chemotherapy these resolved, but 5 months later the patient developed Lambert Eaton syndrome which responded to 3,4-diaminopyridine. This sequence of changes appears to be unique.
一名肺癌小细胞癌患者出现了无症状性自主神经病变、抗利尿激素（ADH）分泌异常和兰伯特-伊顿肌无力综合征。在肿瘤诊断时就已存在自主神经病变和ADH分泌异常。化疗后这些症状有所缓解，但5个月后患者出现了兰伯特-伊顿综合征，该综合征对3,4-二氨基吡啶有反应。这一系列变化似乎是独一无二的。
