单细胞水平下通过李斯特菌 Agr 系统表达证实存在自动诱导异质性。
Evidence of autoinduction heterogeneity via expression of the Agr system of Listeria monocytogenes at the single-cell level.
机构信息
Université de Bourgogne, UMR 1229, F-21000 Dijon, France.
出版信息
Appl Environ Microbiol. 2011 Sep;77(17):6286-9. doi: 10.1128/AEM.02891-10. Epub 2011 Jul 1.
Abstract
To investigate if the primary function of the Agr system of Listeria monocytogenes is to monitor cell density, we followed Agr expression in batch cultures, in which the autoinducer concentration was uniform, and in biofilms. Expression was heterogeneous, suggesting that the primary function of Agr is not to monitor population density.
摘要
为了探究李斯特菌 Agr 系统的主要功能是否是监测细胞密度，我们在自动诱导物浓度一致的分批培养物和生物膜中跟踪 Agr 的表达情况。表达具有异质性，这表明 Agr 的主要功能不是监测种群密度。
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