Nat Cell Biol. 2011 Jul 1;13(7):738-40. doi: 10.1038/ncb0711-738.
Microtubule-depolymerizing motor proteins regulate microtubule dynamics during chromosome segregation, but whether they can independently grip the ends of shrinking kinetochore microtubules has remained unresolved. MCAK, a member of the kinesin-13 motor protein family, is now shown to grip microtubules on its own and harness the forces of microtubule disassembly.
微管解聚驱动蛋白在染色体分离过程中调节微管动力学，但它们是否能够独立地抓住正在收缩的动粒微管的末端一直悬而未决。现在表明，驱动蛋白-13 家族的成员 MCAK 可以自行抓住微管，并利用微管解聚的力。
