Joya Xavier, Fríguls Bibiana, Simó Marta, Civit Ester, de la Torre Rafael, Palomeque Antonio, Vall Oriol, Pichini Simona, Garcia-Algar Oscar
Unitat de Recerca Infancia i Entorn (URIE), Institut Municipal d'Investigació Mèdica (IMIM)-Hospital del Mar, Barcelona, Spain.
J Med Case Rep. 2011 Jul 5;5:288. doi: 10.1186/1752-1947-5-288.
Acute intoxication with drugs of abuse in children is often only the tip of the iceberg, actually hiding chronic exposure. Analysis using non-conventional matrices such as hair can provide long-term information about exposure to recreational drugs.
We report the case of a one-month-old Caucasian boy admitted to our pediatric emergency unit with respiratory distress and neurological abnormalities. A routine urine test was positive for opiates, suggesting an acute opiate ingestion. No other drugs of misuse, such as cocaine, cannabis, amphetamines or derivatives, were detected in the baby's urine. Subsequently, hair samples from the baby and the parents were collected to evaluate the possibility of chronic exposure to drug misuse by segmental analysis. Opiates and cocaine metabolites were detected in hair samples from the baby boy and his parents.
In light of these and previous results, we recommend hair analysis in babies and children from risky environments to detect exposure to heroin and other drug misuse, which could provide the basis for specific social and health interventions.
儿童滥用药物急性中毒往往只是冰山一角,实际上隐藏着长期接触的情况。使用毛发等非常规基质进行分析能够提供有关接触消遣性药物的长期信息。
我们报告了一名1个月大的白种男婴,因呼吸窘迫和神经异常被收治入我院儿科急诊室。常规尿液检测显示阿片类药物呈阳性,提示急性阿片类药物摄入。在婴儿尿液中未检测到其他滥用药物,如可卡因、大麻、苯丙胺或其衍生物。随后,采集了婴儿及其父母的毛发样本,通过分段分析评估长期接触药物滥用的可能性。在男婴及其父母的毛发样本中检测到了阿片类药物和可卡因代谢物。
鉴于这些及先前的结果,我们建议对处于危险环境中的婴儿和儿童进行毛发分析,以检测海洛因及其他药物滥用情况,这可为特定的社会和健康干预措施提供依据。