Nandakumar R, Jagdish C, Prathibha C B, Shilpa C, Sreenivas V, Balasubramanya A M, Nayar R C
Department of Otorhinolaryngology and Head and Neck Surgery, St John's Medical College and Hospital, Bangalore, India.
J Laryngol Otol. 2011 Sep;125(9):958-61. doi: 10.1017/S002221511100137X. Epub 2011 Jun 7.
The incidence of acquired laryngeal stenosis is increasing. This retrospective study aimed to assess the long term results of circumferential resection with end-to-end tracheal anastomosis for isolated post-intubation stenosis of the cervical trachea, and to review the relevant literature.
Twelve male and two female patients (aged 16-30 years, mean age 24 years) treated between February 2003 and December 2008 were included. Hospital and office records were reviewed and relevant surgical details recorded.
Indications for tracheal resection anastomosis were post-intubation stenosis (78.57 per cent) and trauma (21.42 per cent). One to five tracheal rings were resected (i.e. 1-2.5 cm of cervical trachea). Tracheal anastomosis was considered successful if the patient remained asymptomatic for 24 months of close follow up (involving regular flexible bronchoscopy and neck X-ray). The anastomotic success rate was 92.85 per cent.
Tracheal resection and end-to-end anastomosis is relatively safe and reliable for definitive treatment of benign tracheal stenosis in appropriate patients. Local application of mitomycin C prevents granulation and aids long term airway patency.
获得性喉狭窄的发病率正在上升。本回顾性研究旨在评估端端气管吻合的环形切除术治疗孤立性颈段气管插管后狭窄的长期效果,并复习相关文献。
纳入2003年2月至2008年12月期间治疗的12例男性和2例女性患者(年龄16 - 30岁,平均年龄24岁)。查阅医院和门诊记录并记录相关手术细节。
气管切除吻合的指征为插管后狭窄(78.57%)和创伤(21.42%)。切除1至5个气管环(即1 - 2.5 cm的颈段气管)。如果患者在密切随访24个月(包括定期纤维支气管镜检查和颈部X线检查)期间无症状,则认为气管吻合成功。吻合成功率为92.85%。
对于合适的患者,气管切除和端端吻合术在良性气管狭窄的确定性治疗中相对安全可靠。局部应用丝裂霉素C可防止肉芽形成并有助于长期气道通畅。