Butts Ryan J, Crean Andrew M, Hlavacek Anthony M, Spicer Diane E, Cook Andrew C, Oechslin Erwin N, Anderson Robert H
Department of Pediatric Cardiology, Medical University of South Carolina, Charleston, USA.
Cardiol Young. 2011 Dec;21(6):623-30. doi: 10.1017/S1047951111000710. Epub 2011 May 24.
Differentiation of the so-called sinus venosus defect from other defects permitting shunting between the atrial chambers remains problematic. The lesion is not a true septal defect, and current theories to explain the existence of the sinus venosus defect fall short. The presence of persistent systemic to pulmonary venous connections has been proposed to explain the existence of the sinus venosus defect.
Clinical histories and radiological findings of six patients are reviewed. Three patients have veno-venous bridges, two have partial anomalous pulmonary venous connections, and one patient has a sinus venosus defect. The clinical information is reviewed, along with current developmental and morphological considerations.
We provide radiographic, developmental, and morphological evidence to support the theory that a so-called sinus venosus defect is the consequence of persistence of foetal systemic to pulmonary veno-venous bridges, rather than of deficiencies in atrial septation.
将所谓的静脉窦缺损与其他允许心房之间分流的缺损区分开来仍然存在问题。该病变并非真正的间隔缺损，目前解释静脉窦缺损存在的理论并不充分。有人提出持续存在的体循环至肺静脉连接可解释静脉窦缺损的存在。
回顾了6例患者的临床病史和影像学检查结果。3例患者存在静脉-静脉桥，2例存在部分性肺静脉异位连接，1例患者存在静脉窦缺损。对临床信息以及当前的发育和形态学因素进行了回顾。
我们提供影像学、发育和形态学证据，以支持这样一种理论，即所谓的静脉窦缺损是胎儿体循环至肺静脉-静脉桥持续存在的结果，而非房间隔形成缺陷所致。
