Hahn C, Weiske R, Arlart I P
Radiologisches Institut, Katharinenhospital, Stadt Stuttgart.
Rofo. 1990 Nov;153(5):580-4. doi: 10.1055/s-2008-1033442.
In mediastinal lymphoadenopathy diagnostic problems arise if lymphomas are of the same density as cardial or vascular structures. For this reason, CT based on contrast enhancement must definitely ensure a significantly greater enhancement of vascular structures than of non-vascular ones during the entire scan period. We studied 4 groups of 20 patients each employing standardised CT examinations employing 100 ml. contrast medium in different concentrations (200 and 300 mg. iodine/ml., respectively) and an injection flow rate of 0.7 and 2.0 ml/s. The results show that higher iodine concentrations produce a significantly greater enhancement in the aorta than a lower iodine concentration independent of the flow rate. Although a lower flow rate slightly delayed the enhancement increase, this was nevertheless higher than 60 HU within a period of 4 minutes. Hence, we recommend to perform contrast enhanced CT of the mediastinum using lower flow rates (0.5-1.0 ml/s.) and a higher contrast medium concentration (300 mg. iodine/ml.).
在纵隔淋巴结病中，如果淋巴瘤与心脏或血管结构密度相同，就会出现诊断问题。因此，基于对比增强的CT在整个扫描期间必须确保血管结构的增强明显大于非血管结构。我们对4组患者进行了研究，每组20例，采用标准化CT检查，分别使用100ml不同浓度（分别为200和300mg碘/ml）的造影剂，注射流速为0.7和2.0ml/s。结果表明，与流速无关，较高的碘浓度在主动脉中产生的增强明显大于较低的碘浓度。尽管较低的流速会稍微延迟增强增加，但在4分钟内仍高于60HU。因此，我们建议使用较低的流速（0.5-1.0ml/s）和较高的造影剂浓度（300mg碘/ml）进行纵隔对比增强CT检查。
