Squier Urological Clinic, Columbia University Medical Center, New York, New York, USA.
Curr Opin Urol. 2011 Sep;21(5):351-5. doi: 10.1097/MOU.0b013e32834962e9.
To review the established literature on renal functional outcomes and related pathologies after surgery for renal cortical tumors.
Recent data support the prevailing notion that radical nephrectomy is associated with higher rates of chronic kidney disease, regardless of the metric used in determining renal function. Furthermore, higher rates of chronic kidney disease in patients receiving radical nephrectomy have been associated with more noncancer deaths and higher rates of cardiovascular mortality.
Patients undergoing radical nephrectomy are at an increased risk of noncancer mortality, and in some cases, cardiovascular events and death. A comprehensive preoperative risk assessment is paramount in managing newly diagnosed patients with small renal masses.
回顾关于肾皮质肿瘤手术后肾功能结果和相关病变的已发表文献。
最近的数据支持这样一种主流观点，即无论用于确定肾功能的指标如何，根治性肾切除术都与更高的慢性肾脏病发生率相关。此外，接受根治性肾切除术的患者慢性肾脏病发生率较高与更多非癌症死亡和更高的心血管死亡率相关。
接受根治性肾切除术的患者有更高的非癌症死亡率，在某些情况下还会发生心血管事件和死亡。对新诊断的小肾癌患者进行全面的术前风险评估至关重要。
