Department of Student Nutrition, National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing, China.
Eur J Clin Nutr. 2011 Dec;65(12):1321-7. doi: 10.1038/ejcn.2011.122. Epub 2011 Jul 6.
BACKGROUND/OBJECTIVES: To develop and cross-validate bioelectrical impedance analysis (BIA) prediction equations of total body water (TBW) and fat-free mass (FFM) for Asian pre-pubertal children from China, Lebanon, Malaysia, Philippines and Thailand.
SUBJECTS/METHODS: Height, weight, age, gender, resistance and reactance measured by BIA were collected from 948 Asian children (492 boys and 456 girls) aged 8-10 years from the five countries. The deuterium dilution technique was used as the criterion method for the estimation of TBW and FFM. The BIA equations were developed using stepwise multiple regression analysis and cross-validated using the Bland-Altman approach.
The BIA prediction equation for the estimation of TBW was as follows: TBW=0.231 × height(2)/resistance+0.066 × height+0.188 × weight+0.128 × age+0.500 × sex-0.316 × Thais-4.574 (R (2)=88.0%, root mean square error (RMSE)=1.3 kg), and for the estimation of FFM was as follows: FFM=0.299 × height(2)/resistance+0.086 × height+0.245 × weight+0.260 × age+0.901 × sex-0.415 × ethnicity (Thai ethnicity =1, others = 0)-6.952 (R (2)=88.3%, RMSE=1.7 kg). No significant difference between measured and predicted values for the whole cross-validation sample was found. However, the prediction equation for estimation of TBW/FFM tended to overestimate TBW/FFM at lower levels whereas underestimate at higher levels of TBW/FFM. Accuracy of the general equation for TBW and FFM was also valid at each body mass index category.
Ethnicity influences the relationship between BIA and body composition in Asian pre-pubertal children. The newly developed BIA prediction equations are valid for use in Asian pre-pubertal children.
背景/目的：为了开发和验证来自中国、黎巴嫩、马来西亚、菲律宾和泰国的亚洲青春期前儿童的生物电阻抗分析（BIA）预测方程，以预测总体水（TBW）和去脂体重（FFM）。
研究对象/方法：从五个国家的 948 名 8-10 岁的亚洲儿童（男 492 名，女 456 名）中收集身高、体重、年龄、性别、通过 BIA 测量的电阻和电抗。使用氘稀释技术作为 TBW 和 FFM 估计的标准方法。使用逐步多元回归分析开发 BIA 方程，并使用 Bland-Altman 方法进行交叉验证。
用于估计 TBW 的 BIA 预测方程如下：TBW=0.231×身高(2)/电阻+0.066×身高+0.188×体重+0.128×年龄+0.500×性别-0.316×泰国人-4.574（R (2)=88.0%，均方根误差（RMSE）=1.3kg），用于估计 FFM 的 BIA 预测方程如下：FFM=0.299×身高(2)/电阻+0.086×身高+0.245×体重+0.260×年龄+0.901×性别-0.415×种族（泰国种族=1，其他种族=0）-6.952（R (2)=88.3%，RMSE=1.7kg）。在整个交叉验证样本中，测量值和预测值之间没有显著差异。然而，用于估计 TBW/FFM 的预测方程在 TBW/FFM 较低水平时倾向于高估，而在 TBW/FFM 较高水平时则倾向于低估。一般方程在各个 BMI 类别中对 TBW 和 FFM 的准确性也是有效的。
种族影响 BIA 与亚洲青春期前儿童身体成分之间的关系。新开发的 BIA 预测方程可用于亚洲青春期前儿童。
