Girish Kl, Rahman Farzan S, Tippu Shoaib R
Department of Oral Pathology & Microbiology, Jaipur Dental College, Jaipur, Rajasthan, India.
J Forensic Dent Sci. 2010 Jul;2(2):63-8. doi: 10.4103/0975-1475.81284.
The recent advances in molecular biology have revolutionized all aspects of dentistry. DNA, the language of life yields information beyond our imagination, both in health or disease. DNA fingerprinting is a tool used to unravel all the mysteries associated with the oral cavity and its manifestations during diseased conditions. It is being increasingly used in analyzing various scenarios related to forensic science. The technical advances in molecular biology have propelled the analysis of the DNA into routine usage in crime laboratories for rapid and early diagnosis. DNA is an excellent means for identification of unidentified human remains. As dental pulp is surrounded by dentin and enamel, which forms dental armor, it offers the best source of DNA for reliable genetic type in forensic science. This paper summarizes the recent literature on use of this technique in identification of unidentified human remains.
分子生物学的最新进展彻底改变了牙科的各个方面。DNA作为生命的语言,无论是在健康还是疾病状态下,都能产生超乎我们想象的信息。DNA指纹识别是一种用于解开与口腔及其疾病状态下表现相关的所有谜团的工具。它在分析与法医学相关的各种情况中越来越多地被使用。分子生物学的技术进步推动了DNA分析在犯罪实验室中的常规应用,以实现快速和早期诊断。DNA是识别身份不明的人类遗骸的绝佳手段。由于牙髓被牙本质和牙釉质包围,形成了牙齿的保护层,它为法医学中可靠的基因类型提供了最佳的DNA来源。本文总结了关于该技术在识别身份不明的人类遗骸方面应用的最新文献。