Department of Orthopaedics and Traumatology, Federal Medical Centre, Owo, Nigeria.
Singapore Med J. 2011 Jun;52(6):436-9.
Brodie's abscess is not a common variant of subacute osteomyelitis; however, when it does occur, the presentation is atypical and usually late. This study aimed to describe the mode of presentation of Brodie's abscess and evaluate the results of surgical treatment in a resource-poor setting.
Over a five-year period, we retrospectively reviewed 20 patients who presented to two tertiary health institutions in south western Nigeria with clinical and radiological features of Brodie's abscess.
Brodie's abscess accounted for just 2 percent of all patients with osteomyelitis. Most patients were adults (mean age 21.5 +/- 7.8 years) and males (75 percent). In the series, the tibia was involved in 50 percent of the cases, the femur in 30 percent, and the radius and fibula each in 10 percent. The diaphyseal part of the long bones was affected in 65 percent of the patients and the metaphysis, in the remaining patients. The average size of the cavities was 3.0 +/- 0.8 cm. 65 percent of the isolates yielded Staphylococcus aureus. All patients were treated by curettage of the abscess cavities, cancellous bone grafting and antibiotics. All patients had satisfactory outcomes, with complete incorporation of the grafts and new bone formation in the cavities. No patient reported any recurrence.
Patients with Brodie's abscess respond well to surgical curettage of the abscess, cancellous bone grafting and antibiotic therapy.
Brodie 脓肿并不是亚急性骨髓炎的常见变异；然而，当它确实发生时，表现是非典型的，通常较晚。本研究旨在描述 Brodie 脓肿的表现模式，并在资源匮乏的环境中评估手术治疗的结果。
在五年期间，我们回顾性地审查了在尼日利亚西南部的两家三级医疗机构就诊的 20 名患者，这些患者具有 Brodie 脓肿的临床和影像学特征。
Brodie 脓肿仅占骨髓炎患者的 2%。大多数患者为成年人（平均年龄 21.5 +/- 7.8 岁）和男性（75%）。在该系列中，50%的病例累及胫骨，30%累及股骨，桡骨和腓骨各占 10%。长骨骨干受累占 65%，其余患者为干骺端受累。脓肿腔的平均大小为 3.0 +/- 0.8cm。65%的分离株产金黄色葡萄球菌。所有患者均接受脓肿腔刮除术、松质骨移植和抗生素治疗。所有患者的治疗效果均令人满意，移植物完全融合，腔内形成新骨。没有患者报告任何复发。
Brodie 脓肿患者对脓肿腔刮除术、松质骨移植和抗生素治疗反应良好。
