Samuel Priya, Brack Andrew, Lam John C
Pharmacy Services, Alberta Health Services, Red Deer, Alberta, Canada.
Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
IDCases. 2024 Apr 27;36:e01977. doi: 10.1016/j.idcr.2024.e01977. eCollection 2024.
Brodie's abscess is a manifestation of subacute to chronic osteomyelitis, characterized as intraosseous abscess formation, usually on the metaphysis of the long tubular bones in the lower extremities of male pediatric patients. Clinically, Brodie's abscess presents with atraumatic bone pain of an insidious onset, with absence of systemic findings. Delay in diagnosis is common, as diagnostic imaging, followed by biopsy for culture and histologic examination are generally required to secure a diagnosis of Brodie's abscess. Treatment of Brodie's abscess is non-standardized, and usually consists of surgical debridement and antibacterial therapy. Despite the variability in therapeutic approaches, outcomes of Brodie's abscess treated with surgery and antibiotics are favourable. Herein we report a case of a delayed diagnosis of Brodie's abscess in the upper extremity of an adult female. While she improved with treatment of Brodie's abscess, the case serves to remind clinicians to consider this entity in adult individuals who present with atraumatic bone pain.
布罗迪脓肿是亚急性至慢性骨髓炎的一种表现,其特征为骨内脓肿形成,通常发生在男性儿科患者下肢长管状骨的干骺端。临床上,布罗迪脓肿表现为隐匿起病的无创伤性骨痛,无全身症状。由于通常需要进行诊断性影像学检查,随后进行活检以进行培养和组织学检查才能确诊布罗迪脓肿,因此诊断延迟很常见。布罗迪脓肿的治疗尚无标准化方案,通常包括手术清创和抗菌治疗。尽管治疗方法存在差异,但手术和抗生素治疗布罗迪脓肿的效果良好。在此,我们报告一例成年女性上肢布罗迪脓肿延迟诊断的病例。虽然她经布罗迪脓肿治疗后病情有所改善,但该病例提醒临床医生,对于出现无创伤性骨痛的成年患者要考虑到这一疾病。