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膀胱白斑病:一例病例报告及文献综述

Leukoplakia of the bladder: a case report and literature review.

作者信息

Kasianandan Amuthanila, Kannan Kurinji

机构信息

The Townsville Hospital, 67, Klewarra Boulevard, Douglas, QLD 4814, Australia.

出版信息

Int Urogynecol J. 2012 Jan;23(1):131-3. doi: 10.1007/s00192-011-1491-3. Epub 2011 Jul 6.

DOI:10.1007/s00192-011-1491-3
PMID:21732098
Abstract

An 81-year-old woman presented with symptoms of recurrent urinary tract infections, urge incontinence and nocturia. Cystoscopy performed revealed a whitish plaque lesion on the fundus and right lateral wall of the bladder. The histology of the biopsy confirmed the diagnosis of leukoplakia vesicae of the bladder. The plan is to follow her up with repeat cystoscopy and biopsy in 6 months. The literature search revealed very little information on the pathogenesis and prognosis of this condition due to its rare occurrence. Analysis of the literature signifies the association of chronic irritation due to recurrent urinary tract infections being the commonest cause of leukoplakia vesicae. The recommended long-term follow-up and surveillance based on the literature review is by cystoscopy with or without biopsy.

摘要

一名81岁女性出现反复尿路感染、急迫性尿失禁和夜尿症状。膀胱镜检查发现膀胱底部和右侧壁有白色斑块病变。活检组织学检查确诊为膀胱白斑。计划在6个月后对她进行复查,重复膀胱镜检查和活检。文献检索发现,由于这种疾病罕见,关于其发病机制和预后的信息非常少。文献分析表明,反复尿路感染引起的慢性刺激是膀胱白斑最常见的原因。根据文献综述,推荐的长期随访和监测方法是进行膀胱镜检查,可进行或不进行活检。

相似文献

1
Leukoplakia of the bladder: a case report and literature review.膀胱白斑病:一例病例报告及文献综述
Int Urogynecol J. 2012 Jan;23(1):131-3. doi: 10.1007/s00192-011-1491-3. Epub 2011 Jul 6.
2
Diffuse Leukoplakia of the Bladder Ostium-Sparing in Patient Treated with Leuprorelin for Breast Cancer.在接受亮丙瑞林治疗乳腺癌的患者中出现的膀胱开口处弥漫性白斑病,未累及开口处
Case Rep Urol. 2021 Jul 27;2021:9970711. doi: 10.1155/2021/9970711. eCollection 2021.
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Leukoplakia of the bladder. A report on 20 cases, including 2 cases progressing to squamous cell carcinoma.膀胱白斑病。20例报告,其中2例进展为鳞状细胞癌。
Br J Urol. 1967 Aug;39(4):461-71. doi: 10.1111/j.1464-410x.1967.tb09829.x.
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Clinical value of vesical leukoplakia and evaluation of the neoplastic risk by mutation analyses of the tumor suppressor gene TP53.膀胱白斑的临床价值及通过肿瘤抑制基因TP53突变分析评估肿瘤风险
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[Clinico-morphological characteristics of bladder leukoplakia].
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引用本文的文献

1
Diffuse Leukoplakia of the Bladder Ostium-Sparing in Patient Treated with Leuprorelin for Breast Cancer.在接受亮丙瑞林治疗乳腺癌的患者中出现的膀胱开口处弥漫性白斑病,未累及开口处
Case Rep Urol. 2021 Jul 27;2021:9970711. doi: 10.1155/2021/9970711. eCollection 2021.
2
Recurrence factors in patients with Keratinizing squamous metaplasia of the bladder after surgical management: a single-center retrospective study.膀胱角化性鳞状化生患者手术治疗后的复发因素:一项单中心回顾性研究
Transl Androl Urol. 2021 Feb;10(2):734-740. doi: 10.21037/tau-20-948.

本文引用的文献

1
[Leucoplakia vesicae in females: diagnosis and treatment].[女性膀胱白斑:诊断与治疗]
Urologiia. 2009 Mar-Apr(2):18-22.
2
Clinical value of vesical leukoplakia and evaluation of the neoplastic risk by mutation analyses of the tumor suppressor gene TP53.膀胱白斑的临床价值及通过肿瘤抑制基因TP53突变分析评估肿瘤风险
Int J Urol. 2006 Aug;13(8):1092-7. doi: 10.1111/j.1442-2042.2006.01503.x.
3
Extensive bilateral renal pelvis, ureter and bladder leukoplakia.广泛双侧肾盂、输尿管及膀胱白斑病。
Int J Urol. 2002 Nov;9(11):653-5. doi: 10.1046/j.1442-2042.2002.00535.x.
4
Progression of leukoplakia of the bladder to squamous cell carcinoma 19 years after complete urinary diversion.
J Urol. 1988 Sep;140(3):603-4. doi: 10.1016/s0022-5347(17)41733-2.
5
A case of vesical leukoplakia.一例膀胱白斑病。
Acta Obstet Gynecol Scand. 1991;70(7-8):623-4. doi: 10.3109/00016349109007929.