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[急性护理环境中早期老年康复的结果与预测因素]

[Outcome and predictors of early geriatric rehabilitation in an acute care setting].

作者信息

Burkhardt H, Burger M

机构信息

IV. Medizinische Universitätsklinik, Geriatrisches Zentrum, Universitätsklinikum Mannheim, Medizinische Fakultät Mannheim, Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.

出版信息

Z Gerontol Geriatr. 2012 Feb;45(2):138-45. doi: 10.1007/s00391-011-0203-4.

Abstract

BACKGROUND

Geriatric assessment and treatment including an interdisciplinary team is a well accepted method to improve functionality and mortality in the elderly. Nevertheless, only little evidence and limited data are available concerning the outcome of this approach in an acute care setting and early rehabilitation.

PATIENTS AND METHODS

All patients included in a comprehensive geriatric program within 1 year were eligible for inclusion in a retrospective chart analysis. Admission to the program was allowed after counseling by an experienced geriatrician applying pre-defined criteria including significant deconditioning, preserved rehabilitation prognosis and/or ongoing instable medical condition requiring an acute care setting. Patients who refused therapy or died within the first week of treatment were excluded. A telephone interview was performed 6 months after patient discharge and data concerning mortality, functional course and quality of life (activities of daily life ADL) were retrieved. All patients were treated in an acute care setting in two geriatric and general internal medicine wards.

RESULTS

A total of 138 patients were included in the program. In 128 cases data concerning the 6 month mortality could be retrieved and 92 patients agreed to participate in a complete telephone interview. Mortality within the early rehabilitation course was 4%, the 6 month mortality however was 28%. Functionality improved during early rehabilitation and a median increment of 10 points in the Barthel index was found (range 0-100). Analysis of individual increments showed high interindividual variability throughout the whole range of the ADL score at the beginning of the treatment. Concerning the 6 month course after hospital discharge functionality remained at a steady median value but showed a large range of both increasing and decreasing ADL values. Analysis of predictors by logistic regression revealed the ADL score on admission to the early rehabilitation program as the predominant predictor overriding other factors such as depression or cognitive impairment. An ADL value ≤15 on admission was a strong predictor for an unfavorable outcome in early rehabilitation defined as death or an ADL increment ≤10. An ADL value ≤15 on admission was also a strong predictor for overall mortality within 6 months. On the other hand an ADL value ≤15 on admission was a strong predictor for a steady or increasing functionality among the survivors of the 6 month postdischarge interval.

CONCLUSIONS

The mortality rate in the early rehabilitation course in this preliminary and observational study was relatively low and may be explained by both the exclusion of patients not surviving the first week of treatment and an effective inclusion algorithm. The high overall 6 month mortality rate may also be explained by the selection of patients focusing on those severely functionally impaired. This subpopulation of elderly inpatients in acute care units reveals a high vulnerability to critical incidents. Besides scale effects there is also a remarkable variability in the 6 month postdischarge course pointing to heterogeneity and different patterns concerning the time course of functionality.

摘要

背景

老年评估与治疗,包括跨学科团队,是一种被广泛认可的改善老年人功能和降低死亡率的方法。然而,关于这种方法在急性护理环境和早期康复中的结果,仅有少量证据和有限数据。

患者与方法

在1年内纳入综合老年项目的所有患者均符合纳入回顾性病历分析的条件。在经验丰富的老年病医生根据预定义标准进行咨询后允许患者进入该项目,这些标准包括明显的身体机能下降、保留的康复预后和/或需要急性护理环境的持续不稳定医疗状况。拒绝治疗或在治疗第一周内死亡的患者被排除。在患者出院6个月后进行电话访谈,并获取有关死亡率、功能进程和生活质量(日常生活活动能力ADL)的数据。所有患者均在两个老年病科和普通内科病房的急性护理环境中接受治疗。

结果

该项目共纳入138例患者。在128例中可获取有关6个月死亡率的数据,92例患者同意参与完整的电话访谈。早期康复过程中的死亡率为4%,然而6个月死亡率为28%。在早期康复期间功能有所改善,Barthel指数中位数增加了10分(范围为0 - 100)。对个体增量的分析显示,在治疗开始时ADL评分的整个范围内个体间差异很大。关于出院后6个月的进程,功能保持在稳定的中位数水平,但ADL值有升有降,范围很大。通过逻辑回归分析预测因素发现,进入早期康复项目时的ADL评分是首要预测因素,超过了诸如抑郁或认知障碍等其他因素。入院时ADL值≤15是早期康复不良结局(定义为死亡或ADL增量≤10)的有力预测因素。入院时ADL值≤15也是6个月内总体死亡率的有力预测因素。另一方面,入院时ADL值≤15是出院后6个月间隔期幸存者中功能稳定或改善的有力预测因素。

结论

在这项初步观察性研究中,早期康复过程中的死亡率相对较低,这可能归因于排除了在治疗第一周内未存活的患者以及有效的纳入算法。总体6个月的高死亡率也可能归因于对功能严重受损患者的选择。急性护理病房中的这一老年住院患者亚群显示出对危急事件的高度脆弱性。除了规模效应外,出院后6个月的进程中也存在显著差异,表明在功能时间进程方面存在异质性和不同模式。

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