Skorniakov V I, Popov A S
Zh Vopr Neirokhir Im N N Burdenko. 1990 Jul-Aug(4):14-6.
The authors studied the activity of xanthine oxidase (XO) and xanthine dehydrogenase (XDG) in the cerebrospinal fluid (CSF) of patients with craniocerebral trauma (CCT). XO and XDG activity in CSF appeared in moderate and severe CCT. XO in CSF was predominantly of cerebral origin. The possible role of XO in activation of lipid peroxidation in CCT is discussed. It is suggested that determination of XO and XDG activity in CSF should be used for evaluating the severity of the trauma.
作者研究了颅脑创伤（CCT）患者脑脊液（CSF）中黄嘌呤氧化酶（XO）和黄嘌呤脱氢酶（XDG）的活性。在中度和重度颅脑创伤患者的脑脊液中出现了XO和XDG活性。脑脊液中的XO主要来源于大脑。讨论了XO在颅脑创伤中激活脂质过氧化反应的可能作用。建议通过测定脑脊液中XO和XDG的活性来评估创伤的严重程度。
