Franke F E, Altmannsberger M, Schachenmayr W
Medizinisches Zentrum für Pathologie, Justus-Liebig-Universität, Giessen, Federal Republic of Germany.
Acta Neuropathol. 1990;80(4):448-52. doi: 10.1007/BF00307701.
This report presents the case of a 74-year-old woman who was simultaneously affected by two highly malignant neoplasms, a metastasizing renal cell carcinoma and a glioblastoma with sarcomatous component. Leptomeningeal metastasis of renal carcinoma is shown to invade the glioblastoma at its margin. Especially in gliomas, "cancer to cancer" phenomenomal are only rarely documented. Support by immunohistochemical data may prove those events to be more frequent than assumed.
本报告介绍了一名74岁女性的病例,她同时患有两种高度恶性肿瘤,一种是转移性肾细胞癌,另一种是具有肉瘤成分的胶质母细胞瘤。肾癌细胞的软脑膜转移显示在胶质母细胞瘤边缘侵犯。特别是在胶质瘤中,“癌至癌”现象仅有很少的记录。免疫组化数据支持可能证明这些事件比预期更频繁。