Language and Literacy Group, Murdoch Childrens Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.
Autism. 2012 Mar;16(2):163-77. doi: 10.1177/1362361311399936. Epub 2011 Jul 6.
Prospective questionnaire data from a longitudinal population sample on children with autism spectrum disorders (ASD), developmental delay, specific language impairment, or typical development (TD), were collected at ages eight, 12 and 24 months, via the Communication and Symbolic Behavior Scale Developmental Profile (CSBS) - Infant Toddler Checklist, and the Actions and Gesture section of the MacArthur-Bates Communicative Development Inventory (CDI):Words and Gestures. The four groups were compared at four years of age to identify whether any early behaviours differentiated the groups. While children with ASD differed from TD children on most social communicative measures by 12 months of age, the only social communication characteristic which could differentiate the children with ASD from the other groups were gesture scores on the CDI at 12 months and the CSBS at 24 months. Significant markers of ASD were identifiable in this community sample at an early age, although discrimination between clinical groups was rarely evident.
前瞻性问卷调查数据来自于一个自闭症谱系障碍（ASD）、发育迟缓、特定语言障碍或典型发育（TD）的纵向人群样本，在 8、12 和 24 个月时通过沟通和象征行为量表发展概况（CSBS）-婴儿和幼儿检查表，以及 MacArthur-Bates 交际发展清单（CDI）的动作和手势部分收集：词语和手势。在四岁时，将这四个组进行比较，以确定是否有任何早期行为可以区分这些组。虽然 ASD 儿童在 12 个月大时在大多数社交沟通方面与 TD 儿童存在差异，但唯一可以将 ASD 儿童与其他组区分开来的社交沟通特征是 12 个月时 CDI 和 24 个月时 CSBS 的手势得分。在这个社区样本中，尽管在临床分组之间很少能明显看出差异，但可以在早期识别出 ASD 的显著标志物。
