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生命体征:2002-2010 年美国结直肠癌筛查、发病和死亡情况。

Vital signs: Colorectal cancer screening, incidence, and mortality--United States, 2002-2010.

出版信息

MMWR Morb Mortal Wkly Rep. 2011 Jul 8;60(26):884-9.

Abstract

BACKGROUND

Screening lowers colorectal cancer (CRC) incidence and mortality. CRC is preventable through the removal of premalignant polyps and is curable if diagnosed early. Increased CRC screening and reduced CRC incidence and mortality are among the Healthy People 2020 objectives.

METHODS

CRC screening data are reported using information from 2002-2010 Behavioral Risk Factor Surveillance System surveys. State-specific CRC incidence and mortality data were drawn from the United States Cancer Statistics. Annual percentage changes (APCs) in incidence and death rates from 2003 to 2007 were calculated by state.

RESULTS

From 2002 to 2010, the percentage of persons aged 50-75 years who were adequately screened for colorectal cancer increased from 52.3% to 65.4%. In 2007, CRC incidence ranged from 34.3 per 100,000 population in Utah to 56.9 in North Dakota; death rates ranged from 12.3 per 100,000 in Utah to 21.1 in the District of Columbia (DC). From 2003 to 2007, CRC incidence declined significantly in 35 states, and mortality declined in 49 states and DC, with APCs ranging from 1.0% per year in Alabama to 6.3% per year in Rhode Island.

CONCLUSIONS

CRC incidence and mortality have declined in recent years throughout the United States, and CRC screening has increased.

IMPLICATIONS FOR PUBLIC HEALTH PRACTICE

Continued declines in incidence and mortality are expected as past and current public health emphasis on the importance of CRC screening become evident with the increase in screening. To ensure these gains continue, CRC screening should be accessible and used as recommended by all eligible persons in the United States.

摘要

背景

筛查可降低结直肠癌(CRC)的发病率和死亡率。通过切除癌前息肉可以预防 CRC,并且如果早期诊断则可以治愈。增加 CRC 筛查以及降低 CRC 的发病率和死亡率是 2020 年健康人群的目标之一。

方法

使用 2002-2010 年行为风险因素监测系统调查的信息报告 CRC 筛查数据。从美国癌症统计数据中获取了各州 CRC 的发病率和死亡率数据。按州计算了 2003 年至 2007 年发病率和死亡率的年百分比变化(APC)。

结果

从 2002 年到 2010 年,年龄在 50-75 岁之间接受结直肠癌充分筛查的人群比例从 52.3%增加到 65.4%。2007 年,CRC 的发病率从犹他州的每 10 万人 34.3 例到北达科他州的 56.9 例不等;死亡率从犹他州的每 10 万人 12.3 例到哥伦比亚特区的 21.1 例不等。从 2003 年到 2007 年,35 个州的 CRC 发病率显著下降,49 个州和哥伦比亚特区的死亡率下降,APC 从阿拉巴马州的每年 1.0%到罗得岛州的每年 6.3%不等。

结论

近年来,美国各地的 CRC 发病率和死亡率均有所下降,并且 CRC 筛查的比例有所增加。

对公共卫生实践的意义

随着过去和当前公共卫生对 CRC 筛查重要性的重视逐渐显现,预计发病率和死亡率将继续下降。为了确保这些收益持续下去,CRC 筛查应在全美所有符合条件的人群中普及并按建议使用。

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