Geerligs H J, Feijlbrief M, Bolk M, Bos C A, Drijfhout J W, Welling G W, Welling-Wester S
Laboratorium voor Medische Microbiologie, Rijksuniversiteit Groningen, The Netherlands.
Arch Virol. 1990;114(3-4):251-8. doi: 10.1007/BF01310754.
Thirty eight human sera, seropositive for herpes simplex virus (HSV) and 56 human sera, seronegative for HSV by immunofluorescence and by ELISA, were investigated for reactivity with a series of overlapping synthetic peptides of HSV type 1 glycoprotein D (gD-1). Thirty four out of the 38 human sera positive for HSV reacted with peptides located between residues 300 and 369; the HSV-negative sera reacted with six of the gD-1 peptides, but with none of the peptides within residues 300 to 369.
通过免疫荧光法和酶联免疫吸附测定法，对38份单纯疱疹病毒（HSV）血清反应阳性的人血清以及56份HSV血清反应阴性的人血清进行了研究，以检测它们与一系列1型单纯疱疹病毒糖蛋白D（gD-1）重叠合成肽的反应性。38份HSV阳性的人血清中有34份与位于第300至369位残基之间的肽发生反应；HSV阴性血清与6种gD-1肽发生反应，但与第300至369位残基内的肽均无反应。
