Shen Hua, Zhou He-Tong, Wu Hong-Fei, Yu Hong-Bo, Li Bao-Jun, Zhang Bin, Lin Jian-Zhong
Department of Urology, BenQ Medical Center, Nanjing Medical University, Nanjing, Jiangsu 210019, China.
Zhonghua Nan Ke Xue. 2011 Jun;17(6):527-30.
To analyze the correlation between the size of prostatic middle lobe hyperplasia and the degree of bladder outlet obstruction (BOO) in patients with benign prostatic hyperplasia (BPH).
This study included 131 BPH patients who presented with dysuria between May 2008 and June 2010. The prostate volume and intravesical prostatic protrusion (IPP) were measured by transabdominal ultrasound, Qmax and detrusor pressure at Qmax (P(det@ Qmax)) detected by urodynamic examination, the obstruction degree and detrusor contractility judged using the LinPURR Figure, and the AG value calculated (AG = P(det@ Qmax) -2Qmax). The degrees of BOO were compared between different groups of IPP by variance analysis, and the prostate volume, IPP and AG values underwent Bivariate correlation analysis.
IPP was highly positively correlated with BOO when it was > 10 mm (r = 0.821, P < 0.01), while PV and BOO had a lower correlation (r = 0.475, P < 0.01). There was also a high positive correlation between IPP and P(det@ Qmax) (r = 0.865, P < 0.01).
A close correlation exists between prostatic middle lobe hyperplasia and BOO, and evaluating IPP by ultrasound is a reliable method to determine the degree of BOO.
分析良性前列腺增生(BPH)患者前列腺中叶增生大小与膀胱出口梗阻(BOO)程度之间的相关性。
本研究纳入了2008年5月至2010年6月间出现排尿困难的131例BPH患者。经腹部超声测量前列腺体积和膀胱内前列腺突出(IPP),尿动力学检查检测最大尿流率(Qmax)和Qmax时的逼尿肌压力(P(det@Qmax)),使用LinPURR图判断梗阻程度和逼尿肌收缩力,并计算AG值(AG = P(det@Qmax) - 2Qmax)。通过方差分析比较不同IPP组之间的BOO程度,并对前列腺体积、IPP和AG值进行双变量相关性分析。
当IPP > 10 mm时,IPP与BOO呈高度正相关(r = 0.821,P < 0.01),而前列腺体积(PV)与BOO的相关性较低(r = 0.475,P < 0.01)。IPP与P(det@Qmax)之间也呈高度正相关(r = 0.865,P < 0.01)。
前列腺中叶增生与BOO密切相关,通过超声评估IPP是确定BOO程度的可靠方法。