Ota Seiichiro, Toyama Hiroshi, Uno Masaki, Kato Masaki, Ishiguro Masanobu, Natsume Takahiro, Ito Fumitaka, Kikukawa Kaoru, Tadokoro Masanori, Ichihara Takashi, Katada Kazuhiro
Department of Radiology, Fujita Health University School of Medicine.
Kaku Igaku. 2011 May;48(2):101-7.
89Sr bremsstrahlung SPECT imaging has been evaluated for detecting the more detailed whole body 89Sr distribution.
89Sr bremsstrahlung whole body planar and merged SPECT images were acquired by using two detectors type SPECT system. Energy window A (100 keV +/- 50%) for planar imaging, and energy window A plus adjacent energy window B (300 keV +/- 50%) for SPECT imaging were set on the continuous spectrum. Those images were compared with 99mTc-H-MDP whole body planar and merged SPECT images. To verify the accumulation obtained by bremsstrahlung whole body planar and merged SPECT image, we made original phantom based on the counts of clinical study imaging.
On 89Sr bremsstrahlung merged SPECT image, focal accumulations were recognized in the parts of 99mTc-H-MDP merged SPECT accumulation. Focal accumulations were much clearer on 89Sr bremsstrahlung merged SPECT imaging than those of whole body planar image of 89Sr bremsstrahlung. In phantom study, counts of each concentration linearly increase as acquisition time and number of rotation increase on planar and SPECT images.
89Sr bremsstrahlung merged SPECT imaging would be useful for detecting the more detailed whole body 89Sr distribution.
对89Sr轫致辐射单光子发射计算机断层显像(SPECT)成像用于检测更详细的全身89Sr分布情况进行评估。
使用双探测器型SPECT系统采集89Sr轫致辐射全身平面图像和融合SPECT图像。在连续能谱上设置用于平面成像的能量窗A(100keV±50%)以及用于SPECT成像的能量窗A加相邻能量窗B(300keV±50%)。将这些图像与99mTc-H-亚甲基二膦酸盐(MDP)全身平面图像和融合SPECT图像进行比较。为验证通过轫致辐射全身平面图像和融合SPECT图像获得的聚集情况,我们根据临床研究成像的计数制作了原始体模。
在89Sr轫致辐射融合SPECT图像上,在99mTc-H-MDP融合SPECT聚集的部位可识别出局灶性聚集。89Sr轫致辐射融合SPECT成像上的局灶性聚集比89Sr轫致辐射全身平面图像上的更清晰。在体模研究中,平面图像和SPECT图像上各浓度的计数随采集时间和旋转次数的增加呈线性增加。
89Sr轫致辐射融合SPECT成像对于检测更详细的全身89Sr分布可能有用。