肝细胞癌：治疗的手术方法综述
Hepatocellular carcinoma: a review of the surgical approaches to management.
作者信息
DuBray Bernard J, Chapman William C, Anderson Christopher D
机构信息
Section of Abdominal Transplantation, Washington University School of Medicine, St. Louis, USA.
出版信息
Mo Med. 2011 May-Jun;108(3):195-8.
Abstract
Hepatocellular carcinoma (HCC) is increasing in incidence in the United States and is strongly associated with chronic liver disease and cirrhosis. Surgical therapy with liver transplantation or resection remains the mainstay of curative therapy for patients with HCC. Therapeutic decisions in patients with HCC are complex and are best approached via a multidisciplinary group of liver transplant and hepatobiliary surgeons, oncologists, and hepatologists. In this manuscript, we review the current surgical management of HCC.
摘要
肝细胞癌（HCC）在美国的发病率正在上升，并且与慢性肝病和肝硬化密切相关。肝移植或肝切除的外科治疗仍然是HCC患者根治性治疗的主要手段。HCC患者的治疗决策很复杂，最好通过肝移植和肝胆外科医生、肿瘤学家和肝病学家组成的多学科团队来进行。在本手稿中，我们回顾了HCC目前的外科治疗方法。
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本文引用的文献
1
Surgical treatment of hepatocellular carcinoma: expert consensus statement.肝细胞癌的外科治疗：专家共识声明。
HPB (Oxford). 2010 Jun;12(5):302-10. doi: 10.1111/j.1477-2574.2010.00182.x.
2
The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM.美国癌症联合委员会：第 7 版 AJCC 癌症分期手册与 TNM 的未来。
Ann Surg Oncol. 2010 Jun;17(6):1471-4. doi: 10.1245/s10434-010-0985-4.
3
Hepatocellular carcinoma in non-cirrhotic liver: a reappraisal.非肝硬化肝脏中的肝细胞癌：再评价。
Dig Liver Dis. 2010 May;42(5):341-7. doi: 10.1016/j.dld.2009.09.002. Epub 2009 Oct 13.
4
Outcomes of neoadjuvant transarterial chemoembolization to downstage hepatocellular carcinoma before liver transplantation.肝移植前新辅助经动脉化疗栓塞使肝细胞癌降期的疗效
Ann Surg. 2008 Oct;248(4):617-25. doi: 10.1097/SLA.0b013e31818a07d4.
5
The timing of liver transplantation after primary hepatectomy for hepatocellular carcinoma: a special reference to recurrence pattern and Milan criteria.肝细胞癌初次肝切除术后肝移植的时机：特别提及复发模式和米兰标准。
Transplantation. 2008 Sep 15;86(5):641-6. doi: 10.1097/TP.0b013e3181814de2.
6
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Transplant Proc. 2008 Jul-Aug;40(6):1972-3. doi: 10.1016/j.transproceed.2008.05.061.
7
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Am J Transplant. 2008 Jun;8(6):1177-85. doi: 10.1111/j.1600-6143.2008.02229.x. Epub 2008 Apr 29.
8
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9
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Am J Transplant. 2007 Nov;7(11):2587-96. doi: 10.1111/j.1600-6143.2007.01965.x. Epub 2007 Sep 14.
10
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J Am Coll Surg. 2007 Jul;205(1):27-36. doi: 10.1016/j.jamcollsurg.2007.03.002.
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