Hildebrand Philipp, Duderstadt Stefanie, Jungbluth Thomas, Roblick Uwe Johannes, Bruch Hans-Peter, Czymek Ralf
Department of Surgery, University of Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
JOP. 2011 Jul 8;12(4):364-71.
Pain is the main symptom of chronic pancreatitis. However, in addition to an improvement in pain symptoms, an increase in the quality of life also influences therapeutic success. The present paper evaluates the influence of surgery on chronic pancreatitis, and the early and late postoperative quality of life.
From March 2000 until April 2005, 51 patients underwent surgical treatment for chronic pancreatitis at our institution.
Thirty-nine (76.5%) patients were operated on according to the Frey procedure and, in 12 (23.5%) patients, a Whipple procedure was performed.
Patient data were documented throughout the duration of the hospital stay. Postoperative follow-up data were recorded retrospectively.
Postoperative follow-up with postoperative pain scores and quality of life were carried out using a standardized questionnaire.
During a median follow-up period of 50 months, an improvement in pain scores was observed in 92.3% of the patients in the Frey group and in 66.7% in the Whipple group. The indices for global quality of life and for physical and emotional status increased in both surgical groups.
For patients with chronic pancreatitis, the decisive factor is the quality of life, particularly concerning pain and metabolic changes. The Frey procedure seems to offer advantages with respect to long-term freedom of pain and low risk of surgery-induced pancreatic insufficiency.
疼痛是慢性胰腺炎的主要症状。然而，除了疼痛症状的改善外，生活质量的提高也会影响治疗效果。本文评估手术对慢性胰腺炎的影响以及术后早期和晚期的生活质量。
2000年3月至2005年4月，我院有51例患者接受了慢性胰腺炎的手术治疗。
39例（76.5%）患者按照弗雷氏手术进行操作，12例（23.5%）患者接受了惠普尔手术。
在患者住院期间记录其数据。术后随访数据进行回顾性记录。
采用标准化问卷对患者进行术后随访，记录术后疼痛评分和生活质量。
在中位随访期50个月时，弗雷氏手术组92.3%的患者疼痛评分有所改善，惠普尔手术组为66.7%。两个手术组的总体生活质量以及身体和情绪状况指标均有所提高。
对于慢性胰腺炎患者，决定性因素是生活质量，尤其是疼痛和代谢变化方面。弗雷氏手术在长期疼痛缓解和手术诱发胰腺功能不全风险较低方面似乎具有优势。
