Sobukawa Hideto, Watanabe Mitsuhiro, Kano Rui, Ito Takaaki, Onozaki Masanobu, Hasegawa Atsuhiko, Kamata Hiroshi
Department of Pathobiology, Nihon University School of Veterinary Medicine, Fujisawa, Kanagawa 252–0880, Japan.
J Vet Med Sci. 2011 Nov;73(11):1527-9. doi: 10.1292/jvms.11-0256. Epub 2011 Jul 8.
Bovine mastitis due to Prototheca zopfii leads to reduced milk production and is difficult to cure. Therefore, prevention is the best approach and this is best achieved through the use of effective disinfectants. The aim of this study was to evaluate the in vitro algaecide efficacy of conventional disinfectants against strains of P. zopfii genotype 1 and 2. The minimal algaecide concentration (MAC) of alkyldiaminoethylglycine hydrochloride, chlorhexidine, dioxide chlorine, povidone iodine and sodium hypochlorous acid against 10 isolates and the type strain (SAG2063(T)) of P. zopfii genotype 1 as well as 10 isolates and the type strain (SAG2021(T)) of P. zopfii genotype 2 were examined using the micro dilution method. This in vitro study indicated that alkyldiaminoethylglycine hydrochloride, chlorhexidine, povidone iodine and sodium hypochlorous acid, but not dioxide chlorine, are effective against both genotypes of P. zopfii.
由威克氏原藻引起的牛乳腺炎会导致产奶量下降且难以治愈。因此，预防是最佳方法，而这最好通过使用有效的消毒剂来实现。本研究的目的是评估常规消毒剂对威克氏原藻基因型1和2菌株的体外杀藻效果。采用微量稀释法检测了盐酸烷基二氨基乙基甘氨酸、洗必泰、二氧化氯、聚维酮碘和次氯酸钠对10株威克氏原藻基因型1菌株及模式菌株（SAG2063(T)）以及10株威克氏原藻基因型2菌株及模式菌株（SAG2021(T)）的最低杀藻浓度（MAC）。这项体外研究表明，盐酸烷基二氨基乙基甘氨酸、洗必泰、聚维酮碘和次氯酸钠对两种基因型的威克氏原藻有效，而二氧化氯无效。
