重组组织型纤溶酶原激活剂治疗急性缺血性脑卒中
Recombinant tissue plasminogen activator for the treatment of acute ischemic stroke.
作者信息
Roth Jennifer M
机构信息
Department of Pharmacy Services, Baylor University Medical Center at Dallas.
出版信息
Proc (Bayl Univ Med Cent). 2011 Jul;24(3):257-9. doi: 10.1080/08998280.2011.11928729.
Abstract
The use of recombinant tissue plasminogen activator (rtPA) has been the standard of care for treatment of acute ischemic stroke for several years. Studies evaluating the efficacy, safety, and optimal timing of rtPA use are ongoing. Recently, results of new studies led to expansion of the short timeframe from stroke symptom onset in which a patient can receive this treatment. Additionally, more data are available to support the current goals of administration of rtPA to eligible patients as quickly as possible, as earlier treatment has been proven to improve outcomes.
摘要
多年来，重组组织型纤溶酶原激活剂（rtPA）的使用一直是急性缺血性中风治疗的护理标准。评估rtPA使用的疗效、安全性和最佳时机的研究正在进行中。最近，新研究结果导致可接受该治疗的患者从出现中风症状开始的短时间范围有所扩大。此外，有更多数据支持尽快将rtPA给予符合条件患者的当前目标，因为已证明早期治疗可改善预后。
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