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腹部放线菌病的临床特征:单中心 15 年经验。

Clinical features of abdominal actinomycosis: a 15-year experience of a single institute.

机构信息

Division of Gastroenterology, Department of Internal Medicine, Seoul St. Mary Hospital, the Catholic University of Korea College of Medicine, Seoul, Korea.

出版信息

J Korean Med Sci. 2011 Jul;26(7):932-7. doi: 10.3346/jkms.2011.26.7.932. Epub 2011 Jun 20.

Abstract

This study was designed to evaluate the clinical features of abdominal actinomycosis and to assess its therapeutic outcome. We reviewed patients with abdominal actinomycosis in Seoul St. Mary hospital, between January 1994 and January 2010. Twenty-three patients (5 male and 18 female, mean age, 47.8 yr; range, 6-75 yr), with abdominal actinomycosis were included. Emergency surgery was performed in 50% due to symptoms of peritonitis. The common presentation on preoperative computerized tomography was a mass with abscess, mimicking malignancy. The mean tumor size was 7.0 cm (range, 2.5-10.5). In all patients, actinomycotic masses were surgically removed. Mean duration of hospital stay was 17.8 days (range, 5-49). Long term oral antibiotic treatment (mean 4.2 months; range, 0.5-7.0 months) were administered to all patients. All patients were free of recurrence after a median follow up of 30.0 months (mean 35.5 ± 14.8 months, range, 10.0-70.0 months); recurrence was not seen in any patient. In conclusion, abdominal actinomycosis should be included as a differential diagnosis when an unusual abdominal mass or abscess presents on abdominal CT. Assertive removal of necrotic tissue with surgical drainage and long term antibiotic treatment provide a good prognosis in patients with actinomycosis.

摘要

本研究旨在评估腹部放线菌病的临床特征,并评估其治疗效果。我们回顾了 1994 年 1 月至 2010 年 1 月期间在首尔圣玛丽医院就诊的腹部放线菌病患者。共纳入 23 例(男 5 例,女 18 例,平均年龄 47.8 岁;范围 6-75 岁)腹部放线菌病患者。由于腹膜炎的症状,50%的患者行急诊手术。术前计算机断层扫描的常见表现为伴有脓肿的肿块,类似于恶性肿瘤。肿瘤平均大小为 7.0 cm(范围 2.5-10.5)。所有患者均行放线菌肿块切除术。平均住院时间为 17.8 天(范围 5-49)。所有患者均接受长期口服抗生素治疗(平均 4.2 个月;范围 0.5-7.0 个月)。所有患者在中位随访 30.0 个月(平均 35.5 ± 14.8 个月,范围 10.0-70.0 个月)后均无复发;无患者出现复发。总之,当腹部 CT 显示不常见的腹部肿块或脓肿时,应将腹部放线菌病作为鉴别诊断。积极切除坏死组织并辅以手术引流和长期抗生素治疗可为放线菌病患者提供良好的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f79/3124725/b92cac6d02ff/jkms-26-932-g001.jpg

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