Verardino Gustavo Costa, Silva Roberto Souto da, Obadia Daniel Lago, Gripp Alexandre Carlos, Alves Maria de Fátima Guimarães Scotelaro
Pedro Ernesto Teaching Hospital, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
An Bras Dermatol. 2011 May-Jun;86(3):537-40. doi: 10.1590/s0365-05962011000300016.
Acrometastasis is a rare occurrence, especially when affecting the hands. It represents around 0.007-0.2% of all metastatic lesions. The most common site of origin is the lung, accounting for 40-50% of all cases reported in the literature. Kidneys and breasts are other sites also associated with neoplastic lesions that disseminate to the hands. More rarely, the site of origin may be the gastrointestinal tract or other systemic tumors or sarcomas. Early diagnosis is difficult, since the condition may be asymptomatic or may mimic tenosynovitis, arthritis, paronychia, pyogenic granuloma or a local infection. In the present paper, the authors report on a patient with the diagnosis of acrometastasis on both hands originating from a basaloid carcinoma of the anal canal. Response to radiotherapy was poor.
肢端转移很少见,尤其是累及手部时。它约占所有转移性病变的0.007 - 0.2%。最常见的原发部位是肺,占文献报道所有病例的40 - 50%。肾脏和乳腺也是与转移至手部的肿瘤性病变相关的其他部位。更罕见的是,原发部位可能是胃肠道或其他全身肿瘤或肉瘤。早期诊断困难,因为这种情况可能无症状,或可能类似腱鞘炎、关节炎、甲沟炎、化脓性肉芽肿或局部感染。在本文中,作者报告了一名双手诊断为肢端转移的患者,其原发于肛管基底样癌。放疗效果不佳。