Hager C M, Cohen P R
Department of Dermatology, Universitat zu Koln, Germany.
Cancer Invest. 1999;17(6):385-90. doi: 10.3109/07357909909021429.
Cutaneous metastases may be the first sign of a previously undiagnosed visceral malignancy or the initial presentation of a recurrent neoplasm. Rarely, skin metastases can resemble a pyogenic granuloma. Three oncology patients who developed new pyogenic granuloma-like cutaneous lesions are described. Histopathologic examination showed metastatic visceral malignancy in the skin. The characteristics of the previously reported cancer patients with metastatic tumor to the skin that mimicked a pyogenic granuloma are reviewed. A biopsy of a skin lesion that clinically appears to represent a pyogenic granuloma should be performed for microscopic examination in patients with a previous visceral malignancy or in cancer-free individuals whose lesions do not resolve after conservative treatment.
皮肤转移瘤可能是先前未被诊断出的内脏恶性肿瘤的首个迹象，或是复发性肿瘤的初次表现。皮肤转移瘤很少会类似化脓性肉芽肿。本文描述了三名肿瘤患者出现了新的化脓性肉芽肿样皮肤病变。组织病理学检查显示皮肤存在转移性内脏恶性肿瘤。本文回顾了先前报道的皮肤转移瘤酷似化脓性肉芽肿的癌症患者的特征。对于有内脏恶性肿瘤病史的患者或保守治疗后病变未消退的无癌个体，若皮肤病变临床看似为化脓性肉芽肿，应进行活检以做显微镜检查。
