Maehara Laura de Sena Nogueira, Mariano Máira Magalhães, Góis Aécio Flávio Teixeira de, Padilha Maria Helena V Q, Yamada Sergio, Porro Adriana Maria
Department of Dermatology from the Medical School of São Paulo -- Federal University of São Paulo (EPM - UNIFESP)-- São Paulo (SP), Brazil.
An Bras Dermatol. 2011 May-Jun;86(3):579-81. doi: 10.1590/s0365-05962011000300026.
Since 1991, eight cases of pulmonary leak capilary syndrome have been described associated with pustular or erythrodermic psoriasis induced or not by the use of acitretin or sirolimus - being one of the cases, fatal. We report the case of a female patient with diagnosed GPP or von Zumbusch and multiple hospitalizations due to such condition. At that time, the condition was evolving with pulmonary onset and resolution with corticosteroids. The patient was not using any previously described medication that could precipitate pulmonary condition (methotrexate and acitretin). This is a rare complication associated with psoriasis which has not been described in Brazilian patients so far.
自1991年以来,已有8例肺漏毛细血管综合征病例被描述,这些病例与使用或未使用阿维A或西罗莫司诱发的脓疱型或红皮病型银屑病相关,其中1例死亡。我们报告1例诊断为泛发性脓疱型银屑病(GPP)或冯·祖姆布施型银屑病的女性患者,因该疾病多次住院。当时,病情以肺部症状起病,并在使用糖皮质激素后缓解。该患者未使用任何先前描述的可引发肺部疾病的药物(甲氨蝶呤和阿维A)。这是一种与银屑病相关的罕见并发症,迄今为止在巴西患者中尚未有过描述。