Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, UNIFESP-EPM.
Braz J Otorhinolaryngol. 2011 Jun;77(3):299-302. doi: 10.1590/s1808-86942011000300005.
Early glottic cancer can be effectively treated with radiation or surgery, but recurrence is a possibility when using any of the treatment modalities.
To assess the outcome of radiotherapy as initial treatment in the control of squamous cell carcinoma of vocal cord (T1) and the effectiveness of salvage surgery (endoscopic or open) after treatment failure.
A retrospective study was based on the analysis of medical records from 43 patients with T1 squamous cell carcinoma of the glottis, radiotherapy as initial treatment and follow-up period of five years.
The rate of recurrence after radiotherapy was 30.2% of the cases, mean diagnosis interval was 29.5 months. As an option for salvage treatment, patients underwent open partial laryngectomy or endoscopic surgery with control rates of 77.7% and 25% respectively.
Our cases showed high rates of recurrence after radiotherapy and open partial laryngectomy was more effective for the salvage surgery.
评估放射治疗作为初始治疗在控制声带鳞状细胞癌（T1）中的作用，以及在治疗失败后进行挽救性手术（内镜或开放）的效果。
本回顾性研究基于对 43 例 T1 声带鳞状细胞癌患者的病历进行分析，这些患者接受了放射治疗作为初始治疗，并进行了 5 年的随访。
放射治疗后复发率为 30.2%，平均诊断间隔为 29.5 个月。作为挽救治疗的一种选择，患者接受了开放性部分喉切除术或内镜手术，其控制率分别为 77.7%和 25%。
我们的病例显示放射治疗后复发率较高，开放性部分喉切除术对挽救性手术更有效。
