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穴位埋线联合西药治疗全身强直阵挛发作型癫痫的疗效观察

[Observation on therapeutic effect of acupoint catgut-embedding combined western medicine for epilepsy of generalized seizures type].

作者信息

Mao Zhong-nan, Gao Zhi-guo, Zhang Guang-wu, Wang Shi-biao

机构信息

Department of Acupuncture and Moxibustion, Jiuquan Hospital of TCM, Jiuquan 735000, Gansu Province, China.

出版信息

Zhongguo Zhen Jiu. 2011 Jun;31(6):509-12.

Abstract

OBJECTIVE

To compare the efficacy differences between acupoint catgut-embedding combined western medicine (ACCWM) and simple western medicine (WM) for treatment of epilepsy of generalized seizures type.

METHODS

Fifty-two patients with epilepsy of generalized seizures type were randomly divided into an ACCWM group (n=30) and a WM group (n=22). Dazhui (GV 14), Yaoshu (GV 2), Jiuwei (CV 15), Qihai (CV 6) were selected in the ACCWM group as the main acupoints combined with routine antiepileptic drugs, Valpromide was taken orally, 2.0 g/d for adult, 50 mg/kg x d for child. The WM group was treated with routine antiepileptic drugs. The epilepsy score and the attack frequency one year before the treatment and one year during treatment were observed and the therapeutic effects in the two groups were compared.

RESULTS

The epilepsy score and the attack frequency were both decreased in the two groups (P<0.01, P<0.05), and the epilepsy score in the ACCWM group decreased significantly (6.57 +/- 3.29 vs 10.73 +/- 2.54, P<0.05). The total effective rate of 90.0% (27/30) in the ACCWM group was superior to that of 68.2% (15/22) in the WM group (P<0.05).

CONCLUSION

The therapeutic effect of ACCWM is superior to that of simple western medicine in treating epilepsy of generalized seizures type. It can improve significantly the attack symptoms so as to enhance life quality of the patients with epilepsy.

摘要

目的

比较穴位埋线联合西药(ACCWM)与单纯西药(WM)治疗全身强直阵挛发作型癫痫的疗效差异。

方法

将52例全身强直阵挛发作型癫痫患者随机分为穴位埋线联合西药组(n = 30)和单纯西药组(n = 22)。穴位埋线联合西药组选取大椎(GV 14)、腰俞(GV 2)、鸠尾(CV 15)、气海(CV 6)为主穴,联合常规抗癫痫药物,丙戊酰胺口服,成人2.0 g/d,儿童50 mg/kg×d。单纯西药组采用常规抗癫痫药物治疗。观察两组治疗前1年及治疗期间1年的癫痫评分及发作频率,并比较两组疗效。

结果

两组癫痫评分及发作频率均降低(P < 0.01,P < 0.05),穴位埋线联合西药组癫痫评分显著降低(6.57 ± 3.29 vs 10.73 ± 2.54,P < 0.05)。穴位埋线联合西药组总有效率为90.0%(27/30),优于单纯西药组的68.2%(15/22)(P < 0.05)。

结论

穴位埋线联合西药治疗全身强直阵挛发作型癫痫的疗效优于单纯西药,能显著改善发作症状,提高癫痫患者生活质量。

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