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精神科医院出院后一年内自杀的风险因素:系统荟萃分析。

Risk factors for suicide within a year of discharge from psychiatric hospital: a systematic meta-analysis.

机构信息

The Euroa Centre, The Prince of Wales Hospital, Barker Street, Randwick, Sydney, New South Wales 2031, Australia.

出版信息

Aust N Z J Psychiatry. 2011 Aug;45(8):619-28. doi: 10.3109/00048674.2011.590465. Epub 2011 Jul 11.

Abstract

BACKGROUND

The increased risk of suicide in the period after discharge from a psychiatric hospital is a well-recognized and serious problem.

OBJECTIVE

The aim of this study was to establish the risk factors for suicide in the year after discharge from psychiatric hospitals and their usefulness in categorizing patients as high or low risk for suicide in the year following discharge.

METHOD

A systematic meta-analysis of controlled studies of suicide within a year of discharge from psychiatric hospitals.

RESULTS

There was a moderately strong association between both a history of self-harm (OR = 3.15) and depressive symptoms (OR = 2.70) and post-discharge suicide. Factors weakly associated with post-discharge suicide were reports of suicidal ideas (OR = 2.47), an unplanned discharge (OR = 2.44), recent social difficulty (OR = 2.23), a diagnosis of major depression (OR = 1.91) and male sex (OR = 1.58). Patients who had less contact with services after discharge were significantly less likely to commit suicide (OR = 0.69). High risk patients were more likely to commit suicide than other discharged patients, but the strength of this association was not much greater than the association with some individual risk factors (OR = 3.94, sensitivity = 0.40, specificity = 0.87).

CONCLUSIONS

No factor, or combination of factors, was strongly associated with suicide in the year after discharge. About 3% of patients categorized as being at high risk can be expected to commit suicide in the year after discharge. However, about 60% of the patients who commit suicide are likely to be categorized as low risk. Risk categorization is of no value in attempts to decrease the numbers of patients who will commit suicide after discharge.

摘要

背景

从精神病院出院后自杀风险增加是一个众所周知且严重的问题。

目的

本研究旨在确定出院后一年内自杀的风险因素,并评估其对患者在出院后一年内自杀风险的分类价值。

方法

对出院后一年内发生自杀的精神病院对照研究进行系统的荟萃分析。

结果

有过自残史(OR=3.15)和抑郁症状(OR=2.70)与出院后自杀有中度强关联。与出院后自杀弱相关的因素包括有自杀想法的报告(OR=2.47)、非计划性出院(OR=2.44)、近期社会困难(OR=2.23)、重度抑郁症诊断(OR=1.91)和男性(OR=1.58)。出院后与服务机构接触较少的患者自杀风险显著降低(OR=0.69)。高风险患者自杀的可能性高于其他出院患者,但这种关联的强度并不比某些个体风险因素(OR=3.94,灵敏度=0.40,特异性=0.87)更强。

结论

没有任何单一因素或多种因素与出院后一年内的自杀有强关联。预计约 3%被归类为高风险的患者在出院后一年内会自杀。然而,约 60%自杀的患者可能被归类为低风险。风险分类对于降低出院后自杀人数没有价值。

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