Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
BMC Public Health. 2011 Jul 8;11:544. doi: 10.1186/1471-2458-11-544.
The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years of age in household contact with a smear and/or culture-positive adult TB case.
This study was a record review of routinely-collected programme data.
A total of 1094 adult TB case folders were reviewed. From all identified contacts, 149 children should have received IPT based on local guidelines; in only 2/149 IPT was initiated. Management of child contacts of sputum smear and/or culture-positive compared to sputum-negative TB patients were similar.
IPT delivery to children remains an operational challenge, especially in high TB-HIV burden communities. A tool to improve IPT management and targeting sputum smear and/or culture-positive TB child contacts may overcome some of these challenges and should be developed and piloted in such settings.
本研究在南非开普敦一个高结核-艾滋病毒负担的基层卫生社区诊所进行。我们描述了对与涂片和/或培养阳性成人结核病例有家庭接触的五岁以下儿童的管理。
这是一项对常规收集的项目数据的记录回顾。
共审查了 1094 份成人结核病例文件夹。根据当地指南，所有确定的接触者中，应给 149 名儿童服用 IPT；但仅在 149 名中启动了 2 名。对痰涂片和/或培养阳性结核患者的儿童接触者的管理与痰涂片阴性患者的管理相似。
向儿童提供 IPT 仍然是一个操作上的挑战，尤其是在高结核-艾滋病毒负担社区。一种用于改进 IPT 管理和针对痰涂片和/或培养阳性结核儿童接触者的工具可能会克服其中的一些挑战，应在这些环境中进行开发和试点。
