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遗传性出血性毛细血管扩张症患者的中风。肺血管畸形重复筛查和早期治疗的新证据：两例报告。

Stroke in hereditary hemorrhagic telangiectasia patients. New evidence for repeated screening and early treatment of pulmonary vascular malformations: two case reports.

机构信息

Service de Neurologie, Centre Hospitalier Universitaire Côte de Nacre, 14033 cedex 9, Caen, France.

出版信息

BMC Neurol. 2011 Jul 9;11:84. doi: 10.1186/1471-2377-11-84.

DOI:10.1186/1471-2377-11-84
PMID:21740592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3148967/
Abstract

BACKGROUND

Paradoxical embolism due to pulmonary arteriovenous malformations is the main mechanism of brain infarction in patients with hereditary hemorrhagic telangiectasia. International Guidelines have recently been published to clarify the performance of screening tests and the effectiveness of treatment for pulmonary arteriovenous malformations.

CASE PRESENTATION

We present two cases of hereditary hemorrhagic telangiectasia patients of our hospital who experienced an acute stroke secondary to paradoxical embolism.

CONCLUSIONS

These two cases show that the guidelines must be followed to prevent the occurrence of ischemic stroke in patients with hereditary hemorrhagic telangiectasia, and that although they may be adequate in most cases, there are some patients who need a more personalized approach.

摘要

背景

遗传性出血性毛细血管扩张症患者的脑梗死主要机制是由于肺动静脉畸形导致的反常栓塞。最近发布了国际指南，以阐明对肺动静脉畸形的筛查试验和治疗效果。

病例介绍

我们介绍了我院两名遗传性出血性毛细血管扩张症患者的病例，他们因反常栓塞而发生急性脑卒中。

结论

这两个病例表明，必须遵循指南以预防遗传性出血性毛细血管扩张症患者发生缺血性脑卒中，尽管在大多数情况下这些指南可能是足够的，但有些患者需要更个性化的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbad/3148967/b601cea0c990/1471-2377-11-84-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbad/3148967/4782b972adc4/1471-2377-11-84-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbad/3148967/b601cea0c990/1471-2377-11-84-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbad/3148967/4782b972adc4/1471-2377-11-84-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbad/3148967/b601cea0c990/1471-2377-11-84-2.jpg

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本文引用的文献

1
International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia.国际遗传性出血性毛细血管扩张症诊断和管理指南。
J Med Genet. 2011 Feb;48(2):73-87. doi: 10.1136/jmg.2009.069013. Epub 2009 Jun 23.
2
Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease).遗传性出血性毛细血管扩张症（伦杜-奥斯勒病）的肺血管表现
Respiration. 2007;74(4):361-78. doi: 10.1159/000103205.
3
Embolotherapy of pulmonary arteriovenous malformations: long-term results in 112 patients.
胸腔镜成功治疗多发性肺动静脉瘘。
Thorac Cancer. 2018 Aug;9(8):1082-1086. doi: 10.1111/1759-7714.12781. Epub 2018 Jun 23.
肺动静脉畸形的栓塞治疗：112例患者的长期结果
J Vasc Interv Radiol. 2004 May;15(5):451-6. doi: 10.1097/01.rvi.0000126811.05229.b6.
4
Pulmonary arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia.遗传性出血性毛细血管扩张症患者的肺动静脉畸形
Am J Respir Crit Care Med. 2004 May 1;169(9):994-1000. doi: 10.1164/rccm.200310-1441OC. Epub 2004 Jan 23.
5
Hereditary haemorrhagic telangiectasia: a population-based study of prevalence and mortality in Danish patients.遗传性出血性毛细血管扩张症：一项基于丹麦患者人群的患病率和死亡率研究。
J Intern Med. 1999 Jan;245(1):31-9. doi: 10.1046/j.1365-2796.1999.00398.x.