Department of Sciences, John Jay College of Criminal Justice, The City University of New York, USA.
J Anal Toxicol. 2011 Jul;35(6):333-40. doi: 10.1093/anatox/35.6.333.
Federal workplace drug testing was initiated during the late 1980s. Since then, numerous methods have been employed to subvert these drug tests, adulteration of urine samples being the most common. A wide variety of adulterants has been reported to date along with suitable methods of their detection. Recently, websites have claimed that zinc sulfate can be an effective adulterant to bypass drug testing. Herein, these claims are investigated using standard drug detection kits and urine samples adulterated with zinc. Drug-free urine samples were fortified with different amounts methamphetamines and benzoylecgonine, to which zinc sulfate was added to study its effect. Urine samples from acute marijuana smokers were also obtained in order to study the effects of zinc supplements on THC drug testing. All urine drug testing was performed using ELISA detection kits manufactured by Immunalysis. Both zinc sulfate and zinc supplements are effective in interfering with the detection of all three drugs by Immunalysis drug detection kits. Also, no suitable method could be established to detect zinc in urine samples. Zinc can be an effective adulterant in urine for some illicit drugs that are commonly screened under routine drug testing.
联邦工作场所药物测试始于 20 世纪 80 年代末。自那时以来，已经采用了许多方法来规避这些药物测试，尿液样本的掺假是最常见的方法。迄今为止，已经报道了各种各样的掺杂物，以及检测它们的合适方法。最近，一些网站声称硫酸锌可以作为一种有效的掺杂物来规避药物测试。在此，使用标准药物检测试剂盒和掺有硫酸锌的尿液样本对这些说法进行了研究。用不同量的冰毒和苯丙胺对无毒品的尿液样本进行了强化，向其中添加了硫酸锌，以研究其效果。还获得了急性大麻吸食者的尿液样本，以研究锌补充剂对 THC 药物测试的影响。所有尿液药物测试均使用 Immunalysis 制造的 ELISA 检测试剂盒进行。硫酸锌和锌补充剂都能有效地干扰 Immunalysis 药物检测试剂盒对所有三种药物的检测。此外，无法建立合适的方法来检测尿液样本中的锌。对于一些在常规药物测试中经常筛选的非法药物，硫酸锌可以作为尿液中的有效掺杂物。
