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先天性皮肤发育不全:早期治疗对颅骨骨生成的影响。

Aplasia cutis congenita: impact of early treatment on calvarial osteogenesis.

机构信息

Hospital de Crânio e Face SOBRAPAR, Institute of Plastic and Craniofacial Surgery, Campinas-SP, Brazil.

出版信息

J Plast Reconstr Aesthet Surg. 2011 Sep;64(9):e237-40. doi: 10.1016/j.bjps.2010.11.011. Epub 2011 Jul 7.

Abstract

We describe an infant with severe aplasia cutis congenita of the scalp that was characterised by a full-thickness calvarial bone defect combined with the absence of dura mater complicated by sagittal sinus haemorrhage. The defect was successfully managed by closure with a local temporal flap combined with a periosteum patch to allow closure of the dura mater. Previously, conservative treatments failed to remedy unexpected, massive bleeding, which could potentially threaten a patient's life. We highlight the osteogenic potential of surgically manipulated dura mater in this patient who was managed early with a surgical approach.

摘要

我们描述了一例头皮严重先天性全层颅骨发育不全的婴儿,其特点是颅骨全层骨缺损,伴有硬脑膜缺失,并发矢状窦出血。该缺损通过使用局部颞部皮瓣和骨膜补丁成功闭合,从而使硬脑膜得以闭合。此前,保守治疗未能纠正意外的大量出血,这可能会威胁患者的生命。我们强调了在这名患者中手术处理硬脑膜的成骨潜力,该患者早期通过手术方法进行了治疗。

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