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大型三级医学中心的阑尾类癌:病理发现和长期随访评估。

Appendiceal carcinoid at a large tertiary center: pathologic findings and long-term follow-up evaluation.

机构信息

Department of General and Oncological Surgery, Chaim Sheba Medical Center, Tel Hashomer, 52621, Israel.

出版信息

Am J Surg. 2011 Jun;201(6):805-8. doi: 10.1016/j.amjsurg.2010.04.016.

Abstract

BACKGROUND

Appendiceal carcinoid tumor is the most common type of primary appendiceal malignant lesion. Nonetheless; it is an exceedingly rare diagnosis; found in only about .3% to .9% of appendectomy specimens. We report the clinical and pathologic characteristics of carcinoids found with long-term follow-up evaluation.

METHODS

Data of patients who were histologically reported to have carcinoid tumor of the appendix; in a single center; during a 16-year period were collected retrospectively. In addition; patients were contacted for current follow-up information.

RESULTS

A total of 44 patients were diagnosed with appendiceal carcinoid during the study period. The median follow-up period for the cohort was 7 years. No evidence of any recurrent disease or other noncarcinoid neoplasm was found.

CONCLUSIONS

Our data confirm the good prognosis as seen in earlier reports. The long-term significance of having a carcinoid; and whether this poses a risk for future neoplasms; need even longer-term studies.

摘要

背景

阑尾类癌是最常见的原发性阑尾恶性病变。尽管如此,它的诊断极为罕见,仅占阑尾切除标本的 0.3%至 0.9%。我们报告了长期随访评估中发现的类癌的临床和病理特征。

方法

我们回顾性地收集了在 16 年内于单中心经组织学报告为阑尾类癌肿瘤的患者数据。此外,我们还联系了患者以获取当前的随访信息。

结果

在研究期间,共有 44 名患者被诊断为阑尾类癌。该队列的中位随访时间为 7 年。未发现任何复发性疾病或其他非类癌性肿瘤的证据。

结论

我们的数据证实了早期报告中所见的良好预后。类癌的长期意义,以及它是否对未来的肿瘤构成风险,需要更长时间的研究。

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