Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Shandong, China.
Carbohydr Res. 2011 Sep 27;346(13):2016-8. doi: 10.1016/j.carres.2011.05.026. Epub 2011 May 30.
Conversion of fructose into furan derivatives 5-hydroxymethylfurfural (HMF) and 5-methoxymethylfurfural (MMF) is performed in tetrahydrofuran (THF) and methanol-organic solvent systems, catalysed by an acidic resin Amberlyst-15. The melted fructose can be converted into HMF on the surface of the solid resin catalyst in the presence of THF as an extracting phase, which is a good solvent for HMF and other by-products. The solid resin catalyst can be reused eleven times without losing its catalytic ability, with an average HMF yield of approximately 50%. Upon the addition of methanol, the generated HMF can further react with methanol to form MMF, and the total yield of HMF and MMF could be promoted to 65%. GC-MS analysis confirms the formation of a small amount of methyl levulinate in methanolorganic solvent system.
果糖在四氢呋喃（THF）和甲醇-有机溶剂体系中转化为呋喃衍生物 5-羟甲基糠醛（HMF）和 5-甲氧基甲基糠醛（MMF），由酸性树脂 Amberlyst-15 催化。熔融的果糖在 THF 作为萃取相的存在下，可以在固体树脂催化剂的表面上转化为 HMF，THF 是 HMF 和其他副产物的良好溶剂。固体树脂催化剂可以重复使用十一次而不失去其催化能力，平均 HMF 收率约为 50%。加入甲醇后，生成的 HMF 可以进一步与甲醇反应生成 MMF，HMF 和 MMF 的总收率可以提高到 65%。GC-MS 分析证实了在甲醇-有机溶剂体系中形成了少量的甲基乙酰丙酸甲酯。
