评估凝血对从山羊血液中回收铜的影响。

An evaluation of the effect of clotting on the recovery of copper from caprine blood.

机构信息

Institute of Veterinary, Animal, Biomedical Sciences, Massey University, Palmerston North, New Zealand.

出版信息

Vet J. 2012 May;192(2):232-5. doi: 10.1016/j.tvjl.2011.06.005. Epub 2011 Jul 8.

DOI:10.1016/j.tvjl.2011.06.005

Abstract

In the goat, diagnosis of copper (Cu) deficiency is often based on measurement of Cu in serum or plasma. Previous research in cattle and sheep has shown that these values are not interchangeable, but data for goats have not been published. Paired serum and heparinised plasma samples taken from 119 goats in eight herds were tested for Cu concentration. Plasma and serum Cu were significantly correlated (r=0.95). On average serum Cu was 3.5 μmol/L lower than plasma Cu, but this difference was related to Cu status (r=0.45). Mean serum Cu concentration was 83% of plasma Cu, with the 95% limits of agreement ranging from 66% to 100%. Similar to cattle and sheep, individual variability in Cu loss during clotting is too great for serum Cu to be used as a measure of Cu status in goats.

摘要

在山羊中，铜（Cu）缺乏症的诊断通常基于血清或血浆中 Cu 的测量。先前在牛和羊中的研究表明，这些值不能互换，但尚未发表有关山羊的数据。从 8 个畜群中的 119 只山羊采集配对的血清和肝素化血浆样本，以检测 Cu 浓度。血浆和血清 Cu 呈显著相关（r=0.95）。平均而言，血清 Cu 比血浆 Cu 低 3.5 μmol/L，但这种差异与 Cu 状态有关（r=0.45）。血清 Cu 的平均浓度为血浆 Cu 的 83%，其一致性界限范围为 66%至 100%。与牛和羊相似，在凝血过程中 Cu 损失的个体变异性太大，因此血清 Cu 不能用作山羊 Cu 状态的衡量标准。