Division of Critical Care, Department of Anesthesiology, University of Michigan Health System, 1500 East Medical Center Drive, SPC 5861, Ann Arbor, MI 48109-5861, USA.
Crit Care Clin. 2011 Jul;27(3):439-58. doi: 10.1016/j.ccc.2011.05.005.
Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are distinctly modern clinical entities. Recent epidemiologic research has taken advantage of large cohorts in efforts to better describe these highly lethal syndromes with a focus on differentiation of clinically meaningful subtypes and early prediction in an effort to improve treatment and prevention. This article identifies the most significant studies and systematic reviews of recent years, defining the incidence, mortality, risk and prognostic factors, and etiologic classes of ARDS/ALI.
急性呼吸窘迫综合征(ARDS)和急性肺损伤(ALI)是明确的现代临床实体。最近的流行病学研究利用大样本队列,努力更好地描述这些高度致命的综合征,重点是区分具有临床意义的亚型和早期预测,以改善治疗和预防。本文确定了近年来最有意义的研究和系统评价,定义了 ARDS/ALI 的发病率、死亡率、风险和预后因素以及病因分类。