骨密度与关节软骨：骨关节炎中复杂关系的四个临床场景。

Bone mineral density and joint cartilage: four clinical settings of a complex relationship in osteoarthritis.

机构信息

Bone and Joint Research Unit, Service of Rheumatology, IIS-Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.

出版信息

Ann Rheum Dis. 2011 Sep;70(9):1523-5. doi: 10.1136/ard.2011.151233. Epub 2011 Jul 7.

DOI:10.1136/ard.2011.151233

Abstract

Experimental and clinical data support the hypothesis that both high and low bone mineral density (BMD) conditions, including osteoporosis, may induce osteoarthritis. However, these conditions do not always predispose to osteoarthritis progression. Four clinical settings could arise from this relationship, and furthermore two phenotypes may be identified whether early osteoarthritis coexists with high or low BMD.

摘要

实验和临床数据支持这样一种假说，即包括骨质疏松症在内的高和低骨矿物质密度（BMD）状况都可能引发骨关节炎。然而，这些状况并不总是导致骨关节炎的进展。从这种关系中可能会出现四种临床情况，而且无论早期骨关节炎是否同时存在高或低 BMD，都可能确定两种表型。